Found 129 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates whether additional regional nerve blocks can reduce pain and anxiety in adults undergoing Mohs micrographic surgery for skin cancers on the face and scalp. Participants will be randomly assigned to one of two study arms: one receiving a placebo nerve block with sterile saline and the other …
This study investigates the use of an investigational medication in comparison to primary surgery for individuals with early stage Cutaneous Squamous Cell Carcinoma (CSCC). This study aims to understand how the investigational medication affects the tumor and the body, as well as the potential side effects that may occur.Participants in …
This study investigates an imaging technique using an investigational medication and a special camera system to detect cancer in patients undergoing surgery for endometrial cancer. The purpose of this study is to assess how well the investigational medication works when used with this imaging technique during surgery.Participants will undergo several …
This study investigates the effects of total ablative therapy compared to usual systemic therapy in patients with limited metastatic colorectal cancer. Colorectal cancer can spread to other parts of the body, and this study focuses on cases where it has spread to up to four sites. Ablative therapy aims to …
This study investigates the use of image-guided surgery with indocyanine green for imaging solid tumors. The purpose is to evaluate the safety and effectiveness of this method compared to the standard surgical care. Patients involved are those with solid tumors or diseased tissue, including benign nodules, which are considered resectable …
The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer …
This study investigates the effectiveness and safety of an investigational medication combined with pembrolizumab compared to a treatment of the physician's choice in patients with triple negative breast cancer. The purpose is to evaluate these treatments in patients who still have invasive disease after surgery and pre-surgical therapy.Participants will receive …
This study investigates treatment options for non-small cell lung cancer (NSCLC), focusing on patients who undergo surgery. The purpose is to determine if adding an investigational medication to pembrolizumab post-surgery is more effective in preventing disease recurrence in patients who did not achieve a pathological complete response (pCR) after initial …
This study investigates the safety and effectiveness of an investigational imaging agent used during lung cancer surgery. The purpose is to see if this agent can help identify cancerous tissue using near-infrared (NIR) imaging. Participants in this study will undergo surgery for lung cancer, and the investigational agent will be …
A single-dose, open-label, dose-escalation Phase 1b study in patients scheduled to undergo minimally invasive surgery (MIS) for known or suspected lung cancer via thoracoscopy (i.e., VATS). Single dose IV administration of Pemofolacianine for Injection, either on the day before surgery or on the day of surgery, with 2 different doses …
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