Found 118 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The main purpose of this study is to determine the rate of positive sentinel lymph nodes (i.e. the closest draining lymph node(s) to the primary melanoma site) and to test whether treatment with pembrolizumab before surgery to remove melanoma reduces the rate of positive sentinel lymph nodes in patients with …
This study is a prospective, open-label, multicenter clinical trial to evaluate the usability of the REVEALTM 475 system in patients treated with bevonescein for nerve visualization during surgery. The purpose is to characterize the feasibility of using the REVEALTM 475 by obtaining surgeon perspective on 1. Illumination and 2. Ease …
This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete response. The primary hypothesis of this study is sacituzumab tirumotecan plus pembrolizumab is superior to pembrolizumab monotherapy with respect to disease free survival (DFS) as assessed by …
The purpose of this study is to compare the usual treatment alone to using one year of olaparib. We will enroll subject who have been diagnosed with pancreatic cancer and have undergone surgery to remove the cancer. Only patients who are found to have a BRCA1, BRCA2 or PALB2 mutation …
This will be a prospective, observational, multicenter study. All implants will be placed in the maxilla or mandible for already established participants at Penn Dental Medicine. The patient will either have a temporary prosthesis placed (out of occlusion) immediately (during the same implant placement visit or within 48 hours) or …
The objective of this study is to obtain neural recordings from deep brain structures while performing simple intraoperative tasks in order to improve the understanding of temporal relationship of deep neural signals and the performance of simple psychomotor, cognitive, and/or executive tasks. The standard DBS surgery provides an opportunity to …
The purpose of this study is to learn if a special type of imaging drug, called a “radioactive tracer” can help doctors see sites of pheochromocytoma or paraganglioma more clearly when used with a procedure called Positron Emission Tomography/Computed Tomography (PET/CT).” Eligible participants will complete the following research procedures: • …
The objective of this study is to establish reasonable assurance of safety and effectiveness to support a premarket application (PMA) to the U.S. FDA for the Cortiva Allograft Dermis, a human acellular dermal matrix (ADM), when used on label as an adjunct in two-stage breast reconstruction. The primary safety endpoint …
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
