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Found 118 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years and younger
All genders
This is a prospective, randomized, controlled, multi-center, clinical trial to demonstrate use of the Nectero East System for stabilization of abdominal aortic aneurysms (AAA) with a maximum diameter of 3.5-5.0 cm. Subjects with AAA will be randomized to either the standard of care control group or the study treatment group …
18-70 years
All genders
Phase 2
The purpose of this study is to evaluate the safety and efficacy of TCD601 (siplizumab), an anti-CD2 monoclonal antibody, in combination with a CNI-free regimen of belatacept, mycophenolic acid (MPA) and corticosteroids compared to a standard of care CNI-based regimen of tacrolimus, ATG, MPA and corticosteroids in de novo renal …
99 years and younger
All genders
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
99 years and younger
All genders
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
 ROADSTER 3: Post-Approval Study of Transcarotid Artery Revascularization in Standard Risk Patients with Significant Carotid Artery Disease - 2022-46
18-79 years
All genders
This post-approval study (PAS) evaluates real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk for adverse events from carotid endarterectomy (a procedure to treat carotid artery disease). The study will enroll up to 400 patients at 30-60 sites …
99 years and younger
All genders
Please refer to section 1 of the protocol document Please refer to section 1 of the protocol document Please refer to section 1 of the protocol document
99 years and younger
All genders
The objectives of the study are:To investigate demographic, clinical, genetic, and environmental factors that contribute to variability in analgesic response to ibuprofen.To compare the inflammatory profile and neutrophil phenotypes between patients who use supplemental opioids and those who do not.To establish a well-phenotyped cohort of subjects, with biobanked samples, that …
99 years and younger
All genders
We are requesting a reliance agreement with an external IRB (Duke University). The purpose is to refine the Lung Transplant (LTx) Textbook Outcome (TO) definition using retrospective clinical data and to build a machine learning algorithm to predict failure to achieve the refined TO for LTx. A retrospective cohort will …
99 years and younger
All genders
The goal of this pilot RCT is to assess the real-world feasibility of undertaking a trial that will randomize isolated CABG surgery patients to default (i.e. obligatory) as-needed (i.e. backup) intraoperative TEE. Trial outcomes will include subject recruitment, feasibility of intervention, incidence gastroesophageal dysfunction, and cardiac surgeon satisfaction with intraoperative …
35-50 years
Female
The purpose of this study is to determine if two surgical procedures, the usual approach of removing the fallopian tubes and ovaries and the other approach of removing the fallopian tubes at this time with the plan to remove the ovaries at a later time, are no different for ovarian …
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