Found 116 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this study is to evaluate the safety and effectiveness of the study device, which is an endoprosthesis (stent) that is used to treat various lesions of the aortic arch and descending thoracic aorta. Lesions might include aortic aneurysm (weakened area of the aorta), dissection (tear in the …
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absence of circulating tumor DNA (ctDNA) after surgery for colon cancer.This study is Enrolling by Invitation only at Lancaster General Health - ABBCI.
Prospective, nonrandomized, multicenter clinical investigation of the NEXUS Aortic Arch Stent Graft System (NEXUS) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with a brachiocephalic trunk native landing zone.
To evaluate if use of the Percepta Nasal Swab test in the diagnostic work up of newly identified pulmonary nodules reduces the number of invasive procedures in the group classified as low-risk by the test and that are benign as compared to a control group managed without a Percepta Nasal …
Establish a scalable reference library of anatomical 3D maps of the thoracic duct in healthy individuals Map lymphatic vessel 3D molecular maps of the tissue sample obtained during thoracic duct-venous re-anastomosis surgery to 3D cross-sectional (MR and/or CT) imaging of the region of interest 3. Coordinate with the HuBMAP Consortium …
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
This phase II trial tests whether adding nivolumab to the usual treatment (encorafenib and cetuximab) works better than the usual treatment alone to shrink tumors in patients with colorectal cancer that has spread to other places in the body (metastatic) or that cannot be removed by surgery (unresectable) and whose …
This phase III trial studies how well pembrolizumab works compared to standard of care observation in treating patients with stage I-III Merkel cell cancer that has been completely removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere …
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. This trial is open to Penn Medicine's Abramson Cancer Center patients only. Please contact the …
The purpose of this research study is to evaluate whether adding stimulation of the subcallosal cingulate white matter using the investigational Infinity Deep Brain Stimulation (DBS) system in treatment of Major Depressive Disorder is safe and beneficial. This study is looking for 6 patients with Major depressive disorder to participate. …
