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Found 129 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 2/3
Interventional
This study investigates the effects of adding an investigational medication, a type of immunotherapy, to chemotherapy before surgery in patients with high-grade upper tract urothelial cancer. Immunotherapy uses substances to stimulate or support the immune system to fight cancer, while chemotherapy uses drugs to kill or slow the growth of …
18 years or above
All genders
Interventional
This study investigates breast cancer. It looks at the effects of an investigational medication given before surgery.The purpose of this study is to evaluate the safety and immune effects of the investigational medication. The study will check how the body responds to the treatment.Who can participate: Adults aged 18 and …
99 years or below
All genders
Collect safety and efficacy data of MMAE in patients ages 40-90 years with a moderately symptomatic convexity chronic subdural hematoma (CSDH). Subjects will be randomized 1:1 to conventional surgery or MMAE treatment and followed for 180 days (+/- 30 days).
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of investigational medications like hydroxychloroquine and avelumab, with or without palbociclib, on early-stage ER+ breast cancer patients. These patients have disseminated tumor cells (DTCs) in their bone marrow after surgery and standard therapy. The purpose is to understand how these medications can target DTCs, which …
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG
18 years - 99 years
All genders
The overall objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery.
TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
18 years - 99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
Destination Therapy Post Approval Study Product Surveillance Registry Platform Addendum and Apogee
99 years or below
All genders
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
Validation of the prospective registry of outcomes in patients electing lung transplantation (PROPEL)
18 years - 99 years
All genders
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
18 years or above
Male
Interventional
The purpose of this study is to investigate the impact of Gene Expression Classifier (GEC) testing on prostate cancer care. This study involves men with newly diagnosed favorable risk prostate cancer. Participants will be assigned to one of two study arms: the intervention arm or the control arm. The control …
18 years or above
All genders
Interventional
This study investigates the treatment of non-muscle invasive bladder cancer. The purpose of this study is to explore the barriers and facilitators affecting treatment compliance and to test a Bacillus Calmette-Guerin (BCG) at-home program. Participants will be divided into two study arms: one focusing on understanding treatment compliance and the …