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Found 129 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years - 50 years
All genders
Interventional
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …
18 years - 99 years
All genders
Interventional
The purpose of this trial is to determine whether Phasix™ Mesh helps prevent incisional hernias that sometimes occur after abdominal surgery by strengthening the closure of the tissue and/or the incision following surgery.
18 years or above
Female
The purpose of this study is to investigate if minimally invasive surgery, called robotic assisted laparoscopy (small incision surgery), is better or worse than open surgery (otherwise known as a laparotomy) when performing a radical hysterectomy for cervical cancer. A radical hysterectomy is surgery to remove the uterus, cervix, the …
45 years - 99 years
All genders
Patients with an epiretinal membrane (ERM) are either referred for vitrectomy, or if their vision is normal are deferred until vision declines. It is unknown if delaying surgery results in worse visual acuity than if surgery is performed earlier. Additionally, a common symptom from an ERM is metamorphopsia. The objective …
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
10 years - 17 years
All genders
Phase 3
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
75 years or below
All genders
Phase 2
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …
18 years - 90 years
All genders
The primary objective of this study is to determine if treatment of the femoral head with core decompression and cell grafting increases the survivorship of the hip when compared to core decompression alone. The secondary objectives are to determine which factors may contribute to the success or failure of these …
99 years or below
All genders
Prospective, multi-center, pivotal study in which data from subjects undergoing treatment with the Duett Vascular Graft System will be analyzed in comparison to historical data from the literature per Helder (2020). The study is designed to evaluate the safety and effectiveness of the Duett Vascular Graft System when functioning as …
99 years or below
All genders
This is a prospective, randomized, controlled, multi-center, clinical trial to demonstrate use of the Nectero East System for stabilization of abdominal aortic aneurysms (AAA) with a maximum diameter of 3.5-5.0 cm. Subjects with AAA will be randomized to either the standard of care control group or the study treatment group …
18 years or above
All genders
Interventional
This study investigates the safety and effectiveness of an investigational endovascular graft system for treating aortic aneurysms. These aneurysms can involve one or more of the major visceral arteries, which supply blood to essential organs.Participants in the study will receive a combination of an investigational endovascular graft and other stent …
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