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Found 118 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years and younger
All genders
The primary objective of this study is to determine if treatment of the femoral head with core decompression and cell grafting increases the survivorship of the hip when compared to core decompression alone. The secondary objectives are to determine which factors may contribute to the success or failure of these …
99 years and younger
All genders
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.
 A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients with Newly Diagnosed or Recurrent Meningiomas
18-99 years
All genders
Phase 3
This study is designed to investigate the safety, diagnostic performance, and clinical usefulness of Gleolan for the real time detection and visualization of meningiomas during tumor resection surgery. Potential patients who sign informed consent will be screened for eligibility before receiving an oral solution of Gleolan 3 hours prior to …
 A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence
18-99 years
All genders
Phase 3
This is a study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes
18-99 years
All genders
The purpose of the funded grant mentioned above is to document the objective psychosocial and quality-of-life (QOL) outcomes of hand transplant compared to other treatment options (e.g. prosthetics, osseointegration, surgical reconstruction) and evaluate these outcomes over time.
99 years and younger
All genders
Prospective, non-randomized, non-blinded, single-arm, multicenter interventional study to assess the safety and effectiveness of AMDS to treat patients with acute DeBakey type I dissection with evidence of radiographic and/or clinical malperfusion, through open surgical repair.
99 years and younger
All genders
PURPOSE/DESCRIPTION: The main objective of this study is to clinically and radiographically compare the periodontal phenotype (hard and soft tissue) post orthodontic movement on surgical sites using a corticotomy-facilitated bone augmentation approach. We will compare sites grafted with collagen matrix and allograft bone graft material (test group) to the surgical …
 Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG
18-99 years
All genders
The overall objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery.
 Intramolecular Imaging with ICG (PRIME)
18-99 years
All genders
Phase 2
Interventional
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
45-85 years
All genders
This study is designed to prospectively collect blood samples and clinical data from subjects that have a suspected advanced adenoma or have been newly diagnosed with colorectal cancer and scheduled for resection surgery, and subjects who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy …
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