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Found 390 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
To determine if blood biomarkers are associated with the development of cancer or cancer recurrence or the development of late effects of interventions to decrease cancer risk (such as prophylactic oophorectomy) in individuals at high risk for the development of breast, ovarian, pancreatic and other cancers based on family history …
99 years or below
All genders
Obtain patient information (name, age, gender, genetic testing information, OncoType Dx recurrence scores, breast cancer diagnosis information (hormone receptor status, TNM, histology), age at diagnosis) collected from the electronic medical record of approximately 70 patients to perform age-matched control analyses.
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates non-small cell lung cancer. This study looks at how adding an investigational medication to the usual treatment affects patients with this condition.The study evaluates the safety and effectiveness of the investigational medication when used with standard treatments. It observes how well the treatment works and any side …
UPCC 15420 Phase I Trial of huCART19-IL18 Cells in Patients with Relapsed or Refractory CD19+ Cancers
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
18 years - 99 years
Female
Phase 2
This research study is being done to study the safety and toxicity of proton whole pelvis radiation, a type of external beam radiation treatment, for gynecologic cancers after surgery. Currently, for such gynecology cancers, Image- guided Intensity Modulated Radiation Therapy (IG-IMRT) is being done after hysterectomy as the standard treatment. …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment for patients with locally advanced non-small cell lung cancer (NSCLC) that cannot be treated with surgery. The purpose is to see if SBRT, which uses precise radiation to target tumors, can improve outcomes when …
UPCC 09321 Whole-Brain Spectroscopy Guided Personalized Mapping Of Transducer Arrays For Glioblastoma Patients Receiving Tumor Treating Fields
22 years or above
All genders
Interventional
This study investigates the effectiveness of personalized mapping techniques for patients with Glioblastoma, a type of brain cancer. The purpose of this study is to compare two different mapping methods used in tumor treating fields (TTFields) therapy, which is a type of electrical therapy that has shown to improve survival …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates the effect of adding radiation therapy to the usual maintenance therapy with an investigational medication in patients with extensive stage small cell lung cancer. This study aims to compare the progression-free survival and overall survival of patients receiving the investigational medication alone versus those receiving it with …
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