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Found 390 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
The objectives of the study are to recruit patients with tumors of the autonomic nervous system and develop an annotated database including tissue samples to facilitate research with the goal of better understanding the genetics and biochemical signaling pathways leading to tumor formation and malignancy. The primary goal of this …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and imaging characteristics of an investigational fluorescence agent in patients undergoing surgery for lung cancer. The purpose is to evaluate how this agent, administered intravenously, helps visualize tumor margins during surgical procedures. The study focuses on patients with a primary diagnosis or high suspicion of …
99 years or below
All genders
This study's primary objective will be to create a database of lung cancer patients treated with immunotherapy agents and to access Remnant (left-over) tissue collected from clinically-indicated procedures/surgery for analyses, to determine factors that predict response to immunotherapy, and/or the toxicity prole of patients treated with immunotherapy.
99 years or below
All genders
The primary objective of this study is to determine the level of regret patients experience following the decision to pursue amputation and how the extent of patient-reported regret varies with respect to indication (neoplasm versus trauma versus infection). Our secondary objective is to examine how patient- and surgeon-specific factors (including …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
18 years or above
All genders
Observational
This study investigates circulating biomarkers in patients with pancreatic adenocarcinoma. The purpose of this study is to collect blood samples from patients to evaluate these biomarkers, which are substances that can be measured in the blood and may provide information about the cancer.Participants will undergo a procedure to collect blood …
UPCC 21317 Detection of Cell-Free Circulating Tumor DNA in Patients with Histopathologically/Molecularly Proven or Radiographically Suspected Glial Tumors
99 years or below
All genders
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
UPCC 04219 Phase 2 Study of Capecitabine-Temozolomide(CapTem) with yttrium-90 Radioembolization in the Treatment of Patients with Unresectable Metastatic Grade 2/3 Neuroendocrine Tumors
18 years or above
All genders
Phase 2
Interventional
This study investigates the treatment of patients with unresectable metastatic neuroendocrine tumors (NETs) that are primarily located in the liver. The purpose of this study is to evaluate the effectiveness and safety of a combination treatment using Capecitabine-Temozolomide (CapTem) and yttrium-90 (Y90) radioembolization.Participants in the study will receive CapTem, which …