Found 390 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of two investigational medications to treat residual triple negative breast cancer. The purpose of this study is to see if the combination of sacituzumab govitecan and atezolizumab can be effective for patients who have residual cancer in the breast or lymph nodes and have circulating …
This study will assess the ex vivo use of established and in-house near-infrared fluorophores for imaging brain tumors. Fluorophores will be topically applied to freshly excised tumor specimens for imaging on the surgical back table. Participants are patients undergoing surgery for CNS tumors who consent to use of their specimens. …
This study investigates the safety and effectiveness of cardiac radioablation compared to repeat catheter ablation for patients with high-risk refractory ventricular tachycardia (VT). This study focuses on patients who have experienced VT recurrence after a previous catheter ablation and are eligible for another ablation procedure.Participants in the study will be …
This study investigates a treatment for patients with somatostatin receptor type 2 (SST2)-expressing neuroendocrine neoplasms (NENs) and other solid tumors. The purpose of this study is to evaluate the safety and effects of an investigational medication in individuals with these conditions.Participants in the study will receive the investigational medication to …
This study investigates the safety and tolerability of an investigational medication in patients with advanced solid tumors and lymphomas. The study is divided into two phases: Phase 1 focuses on finding the maximum tolerated dose of the investigational medication, while Phase 2 evaluates its antitumor activity across different types of …
This study investigates the safety and effectiveness of an investigational medication for individuals with CALR-mutated myeloproliferative neoplasms, which include conditions like essential thrombocythemia (ET) and myelofibrosis (MF). The purpose of this study is to find the best dose and schedule for the investigational medication.Participants will receive the investigational medication either …
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
This study investigates the safety, tolerability, and pharmacokinetics of an investigational medication in participants with myeloproliferative neoplasms. This study is for those who have been previously treated with a JAK inhibitor and have specific types of myeloproliferative neoplasms, such as primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis.Participants in …
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