Found 390 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to investigate relapsed or refractory multiple myeloma. This study investigates the condition in participants who have previously received specific treatments.This study evaluates the safety and tolerability of an investigational medication in participants. It focuses on understanding how the medication is processed by the body …
The purpose of this program is to be able to provide patients with the drug mezigdomide (CC-92480) for the treatment of multiple myeloma. The reason for treating patients using this program is because they fit one or more of the following criteria: Patient has a serious or immediately life-threatening disease …
The purpose of this protocol is to send the pre-collected and shelved DNA samples (parent protocol IRB #376800) from patients fitting the study eligibility requirements for genotyping at the Center for Inherited Disease Research (CIDR) at Johns Hopkins University. The samples will be used in genome-wide association studies (GWAS), which …
This study investigates a limited-duration therapy approach for patients with relapsed refractory multiple myeloma who have shown a very good partial response or better after receiving teclistamab. This study aims to determine if stopping teclistamab treatment after 6 to 9 months is as effective as continuous treatment in preventing disease …
This study investigates the impact of refractory ascites on health-related quality of life and sarcopenia. The purpose of this study is to use new survey tools to measure changes in quality of life for patients with this condition.Participants will complete quality of life questionnaires at the start of the study, …
This study investigates the effectiveness of 'nudges' to clinicians, patients, or both in increasing referrals to and engagement with tobacco use treatment services (TUTS) for people with HIV. The purpose of this study is to compare these strategies to usual care in a four-arm pragmatic cluster randomized clinical trial. The …
This study investigates treatment options for individuals with recurrent or progressive IDH-1 mutant glioma, a type of brain tumor. The purpose is to evaluate the safety and effects of combining an investigational medication with another treatment. Participants will be divided into two phases: a Safety Lead-In phase to determine safe …
The TMD-PRIME study will be a repository for DNA, RNA, plasma, serum, bone, & tissue from patients enrolled at the Penn Center for Temporomandibular Joint Disease (TMD). TMD-PRIME will create a bio-specimen & data repository by integrating efforts of researchers focused on the study of causes, detection, treatment, & prevention …
The purpose of this study is to investigate different biopsy strategies during colonoscopy for patients with Inflammatory Bowel Disease (IBD). This study focuses on two methods: the limited biopsy strategy, which involves taking fewer random biopsies, and the random biopsy strategy, which involves taking more frequent biopsies throughout the colon. …
This study investigates the effects of an investigational medication on patients with myelofibrosis or myelodysplastic syndrome who also have anemia. Participants in the study will receive the investigational medication, and researchers will monitor its safety, tolerability, and how it affects the body, including its impact on anemia. The study includes …
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