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Found 141 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years and younger
All genders
Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands) Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands) Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands)
 Phase Ia/Ib Dose-Escalation and Dose-Expansion Study Evaluating the Safety  Pharmacokinetics  and Activity of GDC-6036 as a Single Agent and in Combination With Other Anti-cancer Therapies in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
18-99 years
All genders
Phase 1
Interventional
This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.
99 years and younger
All genders
Please refer to Section 2 of the full protocol (Study Objectives) Please refer to Section 2 of the full protocol (Study Objectives) Please refer to Section 2 of the full protocol (Study Objectives)
18-99 years
All genders
Phase 2
Interventional
The purpose of this study are to determine the maximum dose of FF-10832 that can be tolerated when taken in combination with pembrolizumab and to determine whether FF10832 taken by itself or in combination with pembrolizumab has anti-tumor activity.
99 years and younger
All genders
The purpose of this study is to compare the usual approach (observation) to using capecitabine and temozolomide. We will enroll patients with High-Risk Pancreatic Neuroendocrine Tumors. We will utilize CIRB as the IRB of Record.
 Study for the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.
18-99 years
All genders
Interventional
The purpose of this study is to continue to collect long term information on the safety of pembrolizumab or pembrolizumab-based combinations that you received or are receiving as part of the protocol you are currently enrolled in, to see how well the drug/s work and how your body reacts to …
99 years and younger
All genders
Primary Objective: a) To measure the proportion of breast cancer patients where Cerianna positron emission tomography (PET)/computed tomography (CT) detection of estrogen receptor (ER) status alters the preexamination intended therapeutic management Secondary Objectives: a) Per subject, to qualitatively assess heterogeneity in tumor Cerianna uptake relative to standard-of-care imaging b) Per …
99 years and younger
All genders
Phase 2
Subjects with Stage III resectable melanoma will receive adjuvant therapy, nivolumab or ipilimumab plus nivolumab, based on whether a pathologic complete response (CR) or near CR (less than 10% viable tumor cells) is achieved with one dose of nivolumab in the neoadjuvant setting followed by surgery.
99 years and younger
All genders
Please refer to Protocol Section 3. (OBJECTIVES AND ENDPOINTS). Please refer to Protocol Section 3. (OBJECTIVES AND ENDPOINTS). Please refer to Protocol Section 3. (OBJECTIVES AND ENDPOINTS).