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Found 76 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
12 years - 85 years
Accepts healthy volunteer
All genders
Phase 1/2
This study investigates the effects of lower doses of cyclophosphamide, a chemotherapy drug, in patients undergoing bone marrow transplants for certain blood cancers. Blood cancers like leukemia and lymphoma can sometimes be treated with a transplant, but there is a risk that the transplanted cells will attack the recipient's body, …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
All genders
Phase 2
Interventional
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
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