Found 76 Lung Disease trials
A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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To compare dependent lung ventilation (as assessed with EIT, vertical center of ventilation (CoV(v)) measure) between extremely preterm infants treated with NIV-NAVA and those treated with NS-NIPPV. To compare global ventilation homogeneity (as assessed with EIT, global inhomogeneity index (GI) measure) between extremely preterm infants treated with NIV-NAVA to those …
This study will analyze the potential lung protective effect of mild therapeutic hypothermia (TH), similar to that used for cardiac arrest, in ICU patients with acute respiratory distress syndrome (ARDS).
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
This study investigates the safety, tolerability, and preliminary effectiveness of an investigational medication, either alone or in combination with another treatment, for patients with advanced solid tumors. The study includes patients with specific types of cancer, such as urothelial cancer and non-small cell lung cancer, who have not responded to …
This is an OLE for all subjects we currently have enrolled in BI 1305-0014 and 1305-0023. Subjects will be on either 9 mg or 18 mg of IP based on results from the current studies. Procedures involve safety labs, lung function testing, clinical labs, ECGs, PEs, AE collection.
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
Identification of actionable genetic alterations is critical to determining the appropriate therapy in unresectable non-small cell lung cancer (NSCLC). Red blood cells (RBCs) may be an abundant and long-lasting reservoir of detectable tumor DNA. A "liquid biopsy," using blood samples from patients with advanced NSCLC to identify targetable mutations from …
This study investigates the effects of an investigational medication on patients with advanced solid tumors that have a KRAS G12D mutation. The purpose is to understand the safety and effectiveness of the investigational medication when used alone and in combination with other treatments.Participants in the study will receive the investigational …
The main purpose of this study is to determine if certain genes, hormones, or other factors predict the risk of developing lung vessel disease in patients with liver disease and whether they determine outcome. Patients in need of a liver transplant evaluation or have portopulmonary hypertension or are suspected of …
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