Found 61 Lung Disease trials
A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The main purpose of this study is to see whether inhaling this combination of drugs in RSP-1502 has an acceptable safety profile and works better compared to inhaling tobramycin alone when treating participants with Cystic Fibrosis and chronic Pseudomonas aeruginosa lung infection. Procedures include spirometry, ECG, sputum collection, and pharmacokinetic …
The Investigation Device Exemption (IDE) study will evaluate the safety of delivering Aliya PEF in patients with metastatic cancer within the lungs or stage IV non-small cell lung cancer NSCLC) who are treatment-naïve and indicated for first-line standard of care (SOC) cancer therapy.
This trial will be testing if adding radiation to the immunotherapy drug atezolizumab for patients with extensive stage small cell lung cancer (ES-SCLC) can improve progression-free survival (phase II) and overall survival (phase III) when compared to atezolizumab alone. We would like to rely on CIRB as the IRB of …
This study is trying to answer the following questions about treating a pulmonary exacerbation: Do participants have the same improvement in lung function and symptoms if they are treated with one type of antibiotic (called beta-lactams or -lactams) versus taking two different types of antibiotics (tobramycin and -lactams)? Is taking …
A Reliance Agreement with Beth Israel Deaconess Medical Center is requested (SMART IRB). Improved mechanical ventilation treatment strategies are needed to improve outcomes in ICU patients with acute respiratory distress syndrome (ARDS). This study compares standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with ARDS. Personalized, precision …
The purpose of this study is to determine if the combination of the three anti-cancer drugs carboplatin, paclitaxel, and ramucirumab is helpful in shrinking tumors or delaying tumor growth in participants with non-small cell lung cancer. This study will also assess whether it is safe to combine these drugs.Participants for …
This phase III trial compares the effect of the combination of ramucirumab and pembrolizumab versus standard of care chemotherapy for the treatment of non-small cell lung cancer that is stage IV or that has come back after a period of improvement (recurrent). Ramucirumab is a monoclonal antibody that may prevent …
Aim: To conduct a pilot open-label study of semaglutide in lung transplant candidates with obesity. - We will get an estimate of recruitment fraction and retention on study drug. - We will determine preliminary effect estimates of change in weight, percent body fat, skeletal muscle mass, and circulating levels of …
This is a phase 3, multi-center, randomized, single dose, open-label study to determine the efficacy of a single dose, 5 mg/kg of ICG (TumorGlow) used with Near Infrared (NIR) fluorescent to detect clinically significant event (CSE) for subjects with suspected metastatic sarcoma to the lung scheduled to undergo thoracic surgery …
The purpose of any research study is to answer questions. The MAYFLOWERS study is being done to look at how pregnancy affects the health of women with cystic fibrosis (CF) and to look at the health of babies born to women with CF. It is expected that most but not …
