Found 76 Lung Disease trials
A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of investigational medications in combination with pembrolizumab, with or without chemotherapy, for people with Stage IV non-small cell lung cancer (NSCLC). The purpose of this study is to evaluate the safety and effectiveness of these treatment combinations in participants who have not previously received treatment …
This study investigates the safety and effectiveness of standard care treatments in patients with a type of lung cancer known as Epidermal Growth Factor Receptor (EGFR)-mutated Non-Small Cell Lung Cancer (NSCLC). The purpose of this study is to observe patients who are receiving standard care treatments, which may include a …
This is an investigator-initiated, open label phase Ib study examining 2nd line atezolizumab and tocilizumab in a cohort of recurrent/metastatic non-small cell lung cancer patients who have received prior immune checkpoint inhibitor therapy with or without other forms of therapy (i.e. chemotherapy, radiation). Patients with driver mutations in EGFR, ALK, …
This study investigates the safety and imaging characteristics of an investigational fluorescence agent in patients undergoing surgery for lung cancer. The purpose is to evaluate how this agent, administered intravenously, helps visualize tumor margins during surgical procedures. The study focuses on patients with a primary diagnosis or high suspicion of …
This study investigates the effectiveness of an investigational medication combined with chemotherapy compared to another treatment with chemotherapy for patients with advanced non-small cell lung cancer. The focus is on those with a specific protein expression called PD-L1. The study aims to understand how well the investigational medication works in …
This study investigates the use of an investigational imaging agent for lung cancer surgery. The purpose of this study is to explore the effectiveness and safety of a single dose of a fluorescence imaging agent administered through intravenous infusion. This agent is used during surgical procedures for patients with Stage …
This study investigates the use of investigational medications for treating metastatic non-small cell lung cancer (mNSCLC) in patients whose tumors express PD-L1. The purpose of this study is to compare the effectiveness and safety of two treatments: one investigational medication and a standard treatment, pembrolizumab. Participants will be randomly assigned …
This study investigates the use of investigational medications for treating advanced or metastatic non-small cell lung cancer (NSCLC) with a specific genetic mutation known as KRAS G12C. The purpose of this study is to compare the effects of calderasib, a targeted therapy, combined with subcutaneous pembrolizumab, against a combination of …
This study investigates treatment options for patients with non-small cell lung cancer (NSCLC) that have mutations in the epidermal growth factor receptor (EGFR) gene. Patients in this study have experienced disease progression despite previous treatment with EGFR tyrosine kinase inhibitors, which are medications that block signals promoting cancer cell growth.Participants …
This study investigates treatments for non-small cell lung cancer (NSCLC). The purpose of this study is to evaluate the effectiveness of investigational agents, alone or in combination with pembrolizumab and chemotherapy, in treating NSCLC. Pembrolizumab is a type of immunotherapy that helps the immune system fight cancer cells. The study …
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