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Found 61 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18-99 years
All genders
Phase 3
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms in subjects newly diagnosed with NTM lung infection caused by MAC who have not started standard treatment. This is an experimental clinical research study, and ALIS is …
99 years and younger
All genders
We are requesting a reliance agreement with an external IRB (Duke University). The purpose is to refine the Lung Transplant (LTx) Textbook Outcome (TO) definition using retrospective clinical data and to build a machine learning algorithm to predict failure to achieve the refined TO for LTx. A retrospective cohort will …
 An Open-label Phase 1/1b Study to Evaluate the Safety and Pharmacokinetics of JNJ-73841937 (Lazertinib)  a Third Generation EGFR-TKI  as Monotherapy or in Combinations With JNJ-61186372  a Human Bispecific EGFR and cMet Antibody in Participants With Advanced Non-Small Cell Lung Cancer
18-99 years
All genders
Phase 1
the purpose of this study is to see if lazertinib and JNJ-61186372 are safe and useful for treating patients with a type of lung cancer called advanced non-small cell lung cancer (NSCLC). Eligible subjects will be those with NSCLC.
 ARISE - Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18-99 years
All genders
Phase 3
The purpose is to validate patient-reported outcomes questionnaire subjects given ALIS (amikacin liposome inhalation suspension) as part of a study treatment regimen for NontuberculousMycobacterial (NTM) Lung Infection. It will also evaluate the safety and efficacy of the study treatments with ALIS, azithromycin, and ethambutol. Targeted population is patients newly diagnosed …
99 years and younger
All genders
This study aims to provide much-needed data regarding how to optimally treat vulnerable older adults with metastatic NSCLC.
18 years and older
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 magnetic resonance imaging (MRI) in diagnosing and predicting treatment outcomes for patients who received endobronchial valve (EBV) therapy to treat chronic obstructive pulmonary disease (COPD). COPD is a disease of the lungs caused most often by …
 S2302 - Comparing two treatments for advanced lung cancer: one without chemotherapy (using a combination of drugs called ramucirumab and pembrolizumab), and the other following the usual care after immunotherapy
All genders
Phase 3
This study compares the impact of using a combination of drugs, ramucirumab and pembrolizumab, versus standard chemotherapy for treating advanced non-small cell lung cancer that is stage IV or recurrent. Ramucirumab blocks new blood vessel growth that tumors need, while pembrolizumab boosts the immune system to fight cancer. The trial …
99 years and younger
All genders
This study is a retrospective and prospective medical record review of patients with NSCLC harboring EGFR ex20ins mutations treated at cancer centers participating in ATOMIC.
99 years and younger
All genders
This study includes a Dose Escalation Part to identify the recommended combination dose (RCD) and a Dose Expansion Part to further evaluate efficacy and safety.
99 years and younger
All genders
This study is an observational study to collect data on individuals with CF who are not on modulators. Data will be collected on lab tests, microbiology results, lung function tests,questionnaires, antibiotic use,