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Found 59 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study to Investigate the Efficacy and Safety of NS-229 in the Treatment of EGPA
18-90 years
All genders
Phase 2
The main purpose of this study is to learn how well the investigational drug NS-229 works and how safe NS-229 is compared with placebo.  An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA) to treat EGPA.   Participants could be in the …
18-99 years
All genders
The aim of the pilot study is to demonstrate feasibility and tolerability of semaglutide in patients with obesity and advanced ILD. 
99 years and younger
All genders
The purpose of this study is to collect clinical data, blood samples (including DNA), and PROs in 2,600 lung transplant candidates, donors, and recipients across the participating LTC centers to create a resource that will support a broad range of future clinical and research objectives. The data collected will support …
 Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI
18-99 years
All genders
Phase 1
The primary outcomes will be to establish the safety and feasibility of inhaled imaging in patients with NSCLCand to develop a robust RT planning protocol incorporating both standard of care metrics and those derived from inhaled imaging
 Utility of Parametric Response Mapping In Allograft Monitoring After Lung Transplant
18-99 years
All genders
The purpose is to investigate whether parametric response mapping measurements in healthy lung allografts can be used for early detection, prognostication, and phenotyping of CLAD. The target population is bilateral lung transplant recipients who are 6 months post-transplant or later and CLAD free at any of the study institutions. At …
 Validation of the prospective registry of outcomes in patients electing lung transplantation (PROPEL)
18-99 years
All genders
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
99 years and younger
All genders
This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV non-small cell lung cancer or that has come back. Rucaparib may stop the growth of tumor cells by blocking some of the enzymes needed …
 Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
18-90 years
All genders
We are investigating if using a special type of non-radiation imaging (inhaled hyperpolarized xenon with MRI) in lung transplant recipients can outperform current standard tests for transplant rejection. Presently, clinical assessments such as pulmonary function testing (PFT) are able to detect rejection of the transplanted lungs, however, they can only …
99 years and younger
All genders
This is a screening study to test patient specimens to determine eligibility for participation in the biomarker-driven and non-matched sub-studies included within the Lung-MAP umbrella protocol.
 ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18-99 years
All genders
Phase 3
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms in subjects newly diagnosed with NTM lung infection caused by MAC who have not started standard treatment. This is an experimental clinical research study, and ALIS is …