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Found 76 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Supporting Evidence-based Responses to Emotional Needs in Emphysema
18 years - 100 years
All genders
Families play an important role in the experiences of patients with chronic illnesses, including chronic obstructive pulmonary disease (COPD). This study aims to identify how an evidence-based coping skills training program, where patients and a support person work together to manage and overcome disease-related distress, can reduce depression and anxiety …
18 years - 80 years
All genders
Phase 1/2
Interventional
This study investigates the feasibility and tolerability of an investigational medication in patients with advanced lung disease. Advanced lung diseases included in the study are interstitial lung disease, sarcoidosis, chronic obstructive pulmonary disease, and pulmonary hypertension. The purpose of this study is to assess whether patients can tolerate the investigational …
18 years or above
All genders
Observational
This study investigates pulmonary hypertension associated with interstitial lung disease (PH-ILD) and interstitial lung disease (ILD).The study focuses on understanding patient characteristics, treatment patterns, and clinical outcomes for PH-ILD. It evaluates the disease progression in ILD patients who are at risk for pulmonary hypertension.Who can participate: Adults aged 18 years …
99 years or below
All genders
Phase 3
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
99 years or below
All genders
This is a platform study to assess the safety and efficacy of investigational products in participants with interstitial lung disease that is secondary to systemic sclerosis.
99 years or below
All genders
We are requesting a reliance agreement for an external IRB to serve as the single IRB. This study will determine the impact of body composition on perioperative and patient-centered outcomes among adults being evaluated for lung transplantation. Pre-transplant, subjects will complete a survey to assess their health-related quality of life …
12 years - 99 years
All genders
Phase 2
The purpose of this study is to see if taking the study drug, Belumosudil, for 52 weeks in addition to your usual care and medication, will prevent Chronic Lung Allograft Dysfunction (CLAD) in participants who have a lung biopsy that shows evidence of rejection or inflammation to the transplanted lung(s). …
18 years or above
All genders
Phase 3
Interventional
This study investigates progressive CLAD in individuals who have undergone bilateral lung transplantation. The purpose of this study is to evaluate the safety and effectiveness of an investigational medication in comparison to a placebo.The study focuses on assessing how well the investigational medication works and its safety in patients who …
18 years or above
All genders
Phase 2
Interventional
This study investigates an investigational gene therapy in adults with cystic fibrosis. The purpose of this study is to assess the safety, tolerability, and preliminary effectiveness of the investigational gene therapy for individuals who cannot use or tolerate CFTR modulator therapy.Participants in the study will receive a single dose of …
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication for preventing CMV in patients who have received heart or lung transplants.The study evaluates the safety and effectiveness of the investigational medication in comparison to standard treatment. It looks at how well patients tolerate the medication and its impact on their …
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