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Found 352 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Please refer to section 2 of the protocol document. Please refer to section 3.2 of the protocol document. Please refer to section 3.3 of the protocol document.
 A Study of DCC-3116 as Monotherapy and Combination Therapy in Patients With MAPK Pathway Mutant Solid Tumors
18 years - 99 years
All genders
Phase 1
Interventional
This is a Phase 1/2, multicenter, open label, study of DCC-3116 as monotherapy, and in combination with trametinib, binimetinib, or sotorasib in patients with advanced or metastatic solid tumors with RAS/MAPK pathway mutation. The study consists of 2 parts, a dose-escalation phase, and an expansion phase.
99 years or below
All genders
The primary hypothesis of this study is that the combination of tocilizumab, atezolizumab , and FSRT will lead to a robust anti-tumor immune response in GBM. This hypothesis is based on strong preclinical data, which has demonstrated (1) critical roles for IL-6 in GBM immune evasion, (2) that targeting IL-6 …
99 years or below
All genders
This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur.
99 years or below
All genders
This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors. We would like to rely on CIRB as the IRB of record for this study.
99 years or below
All genders
Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints).
99 years or below
All genders
To achieve all of our research objectives, we plan to conduct a pilot study of a CDS intervention, exposing half of our clinician sample to the TUT Service+VM condition during cancer care workflow, and comparing important outcome measures to those observed among the half exposed to the current usual care …
 huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer
18 years - 99 years
All genders
Phase 1
This is a Phase I study evaluating the safety and feasibility of lentiviral transduced huCART-meso cells when given in combination with VCN-01 in a 3+3 dose (de)escalation design.
99 years or below
All genders
Please refer to Protocol Section 2.0 (Objectives and Scientific Aims). Please refer to Protocol Section 14.0 (Biostatistics). Please refer to Protocol Section 14.0 (Biostatistics).
 RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY
18 years - 99 years
All genders
Phase 2
This study plans to treat subjects with pembrolizumab by infusion in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma. Radiation therapy is commonly used to treat relapsed/refractory non-Hodgkin lymphoma. Although pembrolizumab is FDA-approved for some cancers, including Hodgkin lymphoma, it is …
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