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Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and effectiveness of an investigational treatment for patients with metastatic triple-negative breast cancer (TNBC) that is PD-L1-negative. The purpose of this study is to evaluate Sacituzumab Govitecan, alone or in combination with Pembrolizumab, in delaying the progression of this cancer.Participants will undergo various study procedures, …
This study investigates the effectiveness and safety of using Tumor Treating Fields (TTFields) in combination with pembrolizumab and platinum-based chemotherapy for treating metastatic non-small cell lung cancer (NSCLC). The purpose of this study is to assess how well patients survive overall and how long they live without the disease getting …
This study investigates the effectiveness of adding investigational medication combinations to the usual chemotherapy in patients with HER2 positive endometrial cancer. The investigational medications, which include monoclonal antibodies like trastuzumab and pertuzumab, target HER2 receptors on cancer cells to block signals for growth and potentially mark the cells for destruction …
This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
This study investigates the effects of lower doses of cyclophosphamide, a chemotherapy drug, in patients undergoing bone marrow transplants for certain blood cancers. Blood cancers like leukemia and lymphoma can sometimes be treated with a transplant, but there is a risk that the transplanted cells will attack the recipient's body, …
This study investigates therapies for glioblastoma, a type of brain cancer. The purpose of this study is to evaluate multiple therapies for newly diagnosed and recurrent glioblastoma using a response adaptive randomization platform. This method assigns participants to different study arms based on their performance, aiming to identify effective treatments …
This study investigates the safety and feasibility of a treatment involving specialized T cells, known as CART-EGFR-IL13Ra2 cells, for patients with recurrent glioblastoma. The study focuses on patients whose tumors have a specific genetic feature called EGFR amplification.Participants in this study will receive an infusion of their own T cells …
This study investigates the safety of using a type of immune cell therapy in patients with glioblastoma. The study will use T cells, which are a type of white blood cell, that have been modified to target specific proteins on cancer cells. These proteins are known as EGFR and IL13Ra2. …
This study investigates the use of behavioral economics and implementation science to improve the delivery of genomic medicine within a diverse health system. The purpose of this study is to explore how non-geneticist clinicians and patients can be encouraged, through nudges, to utilize genetic testing in situations where it can …
The purpose of this study is to investigate potential markers of pancreatic cancer found in the blood. By collecting blood samples from participants, researchers aim to link these markers to medical and health information. This study may provide insights into detecting pancreatic cancer in the blood before other methods can, …
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