Found 352 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161. We would like to rely on WCG IRB as the IRB of record for this study.
Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints).
This is a Phase 1/2a, dose-escalation, multicenter, first-in-human, consecutive-cohort, open-label study of BI-1808, as a single agent and in combination with pembrolizumab in subjects with advanced malignancies, whose disease has progressed after standard therapy. We would like to rely on WCG as the IRB of record for this study.
patients with newly diagnosed breast cancer will undergo a research PET/CT scan using the radiotracer 18F-FTT (FluorThanatrace) to image PARP-1 activity in the tumor. A sub-set of patients will have a second PET/CT scan to evaluate test-retest reproducibility. Tissue will be collected at the time of surgery for additional research …
An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas.
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel inhibitors of active, GTP-bound RAS (RAS[ON]), in combination with other anticancer therapies in patients with gastrointestinal solid tumors.
Primary Objective: a) To measure the proportion of breast cancer patients where Cerianna positron emission tomography (PET)/computed tomography (CT) detection of estrogen receptor (ER) status alters the preexamination intended therapeutic management Secondary Objectives: a) Per subject, to qualitatively assess heterogeneity in tumor Cerianna uptake relative to standard-of-care imaging b) Per …
Assess if cannabis use over time is associated with changes in key Patient Reported Outcomes (PRO) and opioid use over time. We will enroll 600 participants, each site will include 100 cannabis users 100 cannabis non-users diagnosed with cancer in the last 3 years and prescribed opioids. We will collect …
3 OBJECTIVES AND ENDPOINTS Primary and secondary outcomes will be assessed using routinely collected electronic health record data at Penn Medicine Princeton Medical Center, Pennsylvania Hospital, and Penn Medicine Lancaster General Hospital. Exploratory outcomes will be assessed among those consenting to correlative analyses using additional data collected from participant step …
This trial compares the addition of nivolumab to chemotherapy (carboplatin and paclitaxel) versus usual treatment (chemotherapy alone) for the treatment of anal cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor …
