Found 352 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
This phase II trial studies the side effects of chemotherapy and intensity modulated radiation therapy in treating patients with low-risk HIV-associated anal cancer, and nivolumab after standard of care chemotherapy and radiation therapy in treating patients with high-risk HIV-associated anal cancer.
The study will assess the safety, PK, PD, and preliminary efficacy of ABBV-CLS-484 as monotherapy and in combination with a PD-1 targeting agent or with a or a vascular endothelial growth factor receptor tyrosine kinase inhibitor. The trial aims to establish a safe, tolerable, and efficacious dose of ABBV-CLS-484 as …
Primary Objectives Early phase study to collect and characterize FAP expression imaging in suspected fibrotic tissues related to a variety of suspected fibrosis-inducing conditions, including cancers and non-oncologic conditions, using [F-18]-FAPI-74 PET/CT Secondary Objectives To correlate [F-18]-FAPI-74 uptake measures with clinical outcomes after therapeutic intervention, when applicable. To correlate [F-18]-FAPI-74 …
This study is a randomized, open label, multicenter Phase II trial to evaluate the efficacy and safety of botensilimab (a novel Fc enhanced Tree depleting anti-CTLA4) and balstilimab (a novel anti-PD1) relative to ipilimumab and nivolumab in treatment naïve patients with metastatic ccRCC. We would like to rely on WCG …
The study will enrollsubjects who have undergone surgery for stage II or III colorectal cancer and who have residual FFPE tissue available will provide FFPE and whole blood samples. Subjects will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or observation by their treating clinician.The study also …
Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands) Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands) Please refer to Protocol PRT3645-01, Section 5 (Objectives, Endpoints, and Estimands)
The purpose of this study is to compare the usual approach (observation) to using capecitabine and temozolomide. We will enroll patients with High-Risk Pancreatic Neuroendocrine Tumors. We will utilize CIRB as the IRB of Record.
The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer …
The main purpose of this study is to try a new type of laboratory test for COVID-19 (also called SARS-CoV-2 or novel coronavirus). COVID-19 is a new disease, so not enough is known about it yet. This study hopes to collect more information about who is most as risk from …
