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Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and effectiveness of combining two investigational medications, SNDX-5613 and gilteritinib, for treating relapsed or refractory acute myeloid leukemia (AML) with specific genetic mutations. This study focuses on patients whose leukemia has returned or not responded to treatment and who have mutations in the FLT3 gene, …
This study investigates the safety and tolerability of β-hydroxybutyrate (BHB) supplementation in patients receiving standard-of-care anti-CD19 CAR T-cells for the treatment of lymphoma. The purpose of this study is to determine if BHB supplementation, administered orally, affects the gut microbiome and peripheral blood mononuclear cells (PBMCs) in these patients.Participants will …
This study investigates the effects of adding an investigational medication to an existing treatment with ruxolitinib for patients with myelofibrosis. The purpose of this study is to determine if the investigational medication can provide more benefits than ruxolitinib alone for patients who have not responded well to ruxolitinib by itself.Participants …
This study investigates the use of bone marrow transplantation for patients newly diagnosed with severe aplastic anemia (SAA). The study aims to determine if patients with SAA can be effectively treated with a bone marrow transplant as their first therapy option, using donors who are either haploidentical related or unrelated, …
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
This study investigates a treatment approach for renal cell carcinoma that has spread to other parts of the body. The purpose of this study is to evaluate the effectiveness of a specific therapy called total consolidative metastasis-and-primary directed therapy (MPDT) in patients who have shown stable disease or partial response …
This study investigates the effectiveness of two different treatment regimens for patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with conditions such as acute leukemia, chronic myelogenous leukemia, myelodysplasia, and various types of lymphoma. The purpose is to compare the use of Tacrolimus, Methotrexate, and …
This study investigates the safety of an investigational treatment using allogeneic T stem cell memory (Tscm) CAR-T cells in patients with relapsed or refractory Multiple Myeloma (RRMM). The study involves different parts, including dose escalation to find a safe dose and fixed-dose administration to see how the treatment works.Participants will …
This study investigates the safety and efficacy of an investigational medication for patients who require treatment with a product that does not meet commercial release standards but is deemed safe for use in clinical settings. The purpose of this study is to provide access to this investigational medication for patients …
This study investigates the safety of using investigational cord blood units for hematopoietic stem cell transplantation in pediatric and adult patients. The purpose of this study is to monitor and evaluate any infusion-related reactions that occur when these investigational cord blood units are administered.Participants in the study will receive investigational …
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