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Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of bone marrow transplantation for patients newly diagnosed with severe aplastic anemia (SAA). The study aims to determine if patients with SAA can be effectively treated with a bone marrow transplant as their first therapy option, using donors who are either haploidentical related or unrelated, …
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
This study investigates a treatment approach for renal cell carcinoma that has spread to other parts of the body. The purpose of this study is to evaluate the effectiveness of a specific therapy called total consolidative metastasis-and-primary directed therapy (MPDT) in patients who have shown stable disease or partial response …
This study investigates the effectiveness of two different treatment regimens for patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with conditions such as acute leukemia, chronic myelogenous leukemia, myelodysplasia, and various types of lymphoma. The purpose is to compare the use of Tacrolimus, Methotrexate, and …
This study investigates the safety of an investigational treatment using allogeneic T stem cell memory (Tscm) CAR-T cells in patients with relapsed or refractory Multiple Myeloma (RRMM). The study involves different parts, including dose escalation to find a safe dose and fixed-dose administration to see how the treatment works.Participants will …
This study investigates the safety and efficacy of an investigational medication for patients who require treatment with a product that does not meet commercial release standards but is deemed safe for use in clinical settings. The purpose of this study is to provide access to this investigational medication for patients …
This study investigates the safety of using investigational cord blood units for hematopoietic stem cell transplantation in pediatric and adult patients. The purpose of this study is to monitor and evaluate any infusion-related reactions that occur when these investigational cord blood units are administered.Participants in the study will receive investigational …
Please refer to Section 5 (Research question and objectives) of the full study protocol.
The purpose of this study is to improve our understanding of graft-versus-host disease (GVHD) which is a complication that can occur after a bone marrow transplant. Investigators at Mount Sinai and other BMT centers around the world have formed a collaboration to share and study clinical data and blood samples …
This study investigates the impact of assessing physiologic age in patients newly diagnosed with acute myeloid leukemia (AML) who are 50 years or older. The purpose is to understand how evaluating patients' overall health rather than just their chronological age can affect treatment outcomes such as toxicity, early mortality, remission …
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