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Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates head and neck squamous cell carcinoma. The purpose of this study is to evaluate the safety and effectiveness of an investigational medication when used with standard chemotherapy and radiation therapy.The study focuses on assessing how well the investigational medication works with chemoradiation therapy. It evaluates the treatment's …
This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
This study investigates the use of CAR T cells, a type of cell therapy, in treating patients with CD19+ cancers. The purpose of this study is to understand how safe and feasible it is to use these modified cells in patients whose cancer has come back or has not responded …
This study investigates the safety and feasibility of using a type of adoptive cell therapy called CAR T cells in patients with FRa+ cancers. The purpose of this study is to assess how well these modified T cells can be administered directly into the pleural space, which is the area …
This study investigates an investigational medication for women with advanced platinum-resistant epithelial ovarian cancer, including primary peritoneal and fallopian tube cancers. The purpose of this study is to evaluate the safety and effectiveness of the investigational medication in treating these types of cancers, which are known for being difficult to …
This study investigates the use of frailty assessments to predict outcomes for patients aged 60 years and older who are receiving treatments such as chemotherapy, CAR T-cell therapy, or allogeneic stem cell transplant for blood cancers. Frailty assessments help determine a patient's physical resilience and vulnerability, which may influence treatment …
This study investigates metastatic castration-resistant prostate cancer (mCRPC). The purpose of this study is to compare the effectiveness of an investigational medication, ifinatamab deruxtecan, against standard chemotherapy in extending the lives of participants and delaying cancer progression.Participants in the study will receive either the investigational medication or chemotherapy. The study …
This study investigates the effectiveness of active surveillance and chemotherapy in treating germ cell tumors. The purpose of this study is to see if monitoring patients who have low-risk tumors after surgery can help maintain high survival rates without immediate further treatment. The study also aims to determine whether carboplatin …
This study investigates a treatment for liver metastases from neuroendocrine tumors. It aims to find the best dose and safety of a hypoxia-activating agent combined with embolization, a procedure that blocks blood flow to cancer cells. The agent, administered directly into the liver's arteries, is evaluated using MRI scans based …
To create a comprehensive system to collect, catalogue, and store biological specimens (tumor samples) from subjects with confirmed or suspected pancreatic cancer for future research use. To generate "tumor organoids" from these biopsy or surgical specimens. To integrate the specimen collections with clinical data to permit the most informative clinical- …
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