Clinical Research
Opportunities

Penn Medicine is conducting studies to develop new ways to prevent, diagnose, and treat disease. You might be eligible to participate

Get Started

Clinical Research Opportunities

Penn Medicine is conducting studies to develop new ways to prevent, diagnose, and treat disease. You might be eligible to participate

Get started

Penn Medicine is conducting studies to develop new ways to prevent, diagnose, and treat disease. You might be eligible to participate

Get started

Penn Medicine is conducting medical studies to develop new diagnostic and clinical treatments to improve current standards of care.

Search by keywords

Please select a valid location from the dropdown

Browse by Condition or Investigator

Browse all Trials

Featured
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
All

Featured
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
All

Featured
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
All

Featured studies

UPCC 31920 Penn Medicine BioBank

The Penn Medicine Biobank is collecting and storing biological specimens such as blood, as well as health information from volunteers. These samples and this information allow researchers to use them for research studies including but not limited to COVID-19, cancer, diabetes, and heart disease.

View Details

The GRoceries Aimed at Increasing Nutrition Study (GRAIN Study)

We are looking for adults ages 45-70 to take part in an 18-week study about people‘s online grocery shopping habits. You’ll get a free Walmart+ membership for your grocery deliveries and receive $10 back on all weekly orders over $35. You may earn over $200 in total for completing study …

View Details

Adult Virome Study

Did you know that all of us, including all healthy people, have viruses in our bodies that do not make us sick but actually may contribute to health? Researchers are exploring the viruses that exist in people that are not currently sick in order to understand their role in human …

View Details

Click & Pick Study

The University of Pennsylvania is conducting a 6-week research study to learn about your experience using online grocery stores and online restaurant ordering applications.

View Details

MethaLoad Dose-Finding Study

You may qualify for a paid research study that tests a new way of starting methadone for people using fentanyl. The standard approach to starting methadone uses low doses that increase slowly over time. This study tests whether a higher starting dose, called a loading dose, works better by reducing …

View Details

Recently Added/Updated trials

RE-AHFIRM

99 years or below

All genders

The primary purpose of this study is to evaluate the safety and efficacy of larsucosterol, as determined by transplant-free survival through Day 90 in participants with severe alcohol-associated hepatitis (AH) with pre-treatment Maddrey Discriminant Function (MDF) score greater than or equal to (>=) 32 and Model for End-stage Liver Disease (MELD) scores 21-30, inclusive.

Learn More

LIFU for CUD

99 years or below

All genders

This is a feasibility study looking at Low Intensity Focused Ultrasound treatment to the ventral striatum in patients with cocaine use disorder.

Learn More

ORKA 001-113 Open Label Extension (OLE)

99 years or below

All genders

This study is for adults with moderate-to-severe plaque psoriasis who have already participated in a previous Oruka Therapeutics study and choose to continue receiving ORKA-001 treatment. Participants may stay in the extension study for up to about 96 weeks and will then be followed for about 48 weeks after their last treatment visit.

Learn More

IMPROVE-PAH

99 years or below

All genders

The goal of this study is to evaluate the efficacy and safety of IKT-001 treatment versus placebo in addition to background pulmonary arterial hypertension (PAH) therapy in adults with World Health Organization (WHO) Group 1 PAH. This is a 2-part randomized double blind placebo-controlled trial with a 24-week treatment period that consists of 6 outpatient visits, and the 24-week Extended DBPC.

Learn More

CnF-DBS for Levodopa-Resistant FOG

99 years or below

All genders

This is a multi-site, prospective, randomized, sham-controlled, crossover, double-blinded feasibility clinical trial assessing the extent to which cuneiform nucleus deep brain stimulation (CnF DBS) can ameliorate freezing of gait (FOG) in Parkinsons Disease (PD) patients with severe, Levodopa-resistant gait freezing.

Learn More

Volunteer Sign-Up

If you don’t see a trial that fits your needs, consider joining our research volunteer registry. By signing up, you’ll be notified if a study matches your background and health profile.

Healthy Volunteers

Clinical research studies currently seeking healthy individuals.

View Studies

Virtual Studies

Also called Online or Decentralized studies. Some may be a mix of remote and in-person visits.

View Studies

Penn Medicine Logo Small

Penn Medicine experts answer questions from patient advocates and share groundbreaking medical developments happening at the University of Pennsylvania.