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Found 15 addictions trials

A listing of addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Naltrexone in AUD Reward Drinkers
18 years - 65 years
All genders
Phase 4
Interventional
This study investigates the effectiveness of an investigational medication for individuals who are primarily reward drinkers, meaning they drink for the positive effects of alcohol. The purpose is to determine if these individuals are more likely to reduce heavy drinking when receiving the investigational medication compared to a placebo. The …
General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders
18 years - 64 years
All genders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.
18 years - 75 years
Accepts healthy volunteer
All genders
The goal is to conduct a screening procedure to be used in evaluating individuals either with or without an alcohol use disorder (AUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, genetic study, or other research protocol that matches their …
Psilocybin: Motivation and Neurocognition in Individuals with Opioid Use Disorder
18 years - 60 years
All genders
This study is testing a substance called psilocybin to see how it affects the brain and thinking in people who are recovering from opioid addiction. Psilocybin is the main ingredient in “magic mushrooms.” In the body, it turns into a chemical called psilocin, which affects the brain's serotonin system. This …
Integrating Brain, Neurocognitive, and Computational Tools in Opioid Use Disorder (OUD) to Characterize Executive Function and to Predict Clinical Outcomes
18 years - 60 years
Accepts healthy volunteer
All genders
Phase 3
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on executive function and clinical outcomes.
Rapid outpatient low-dose initiation of buprenorphine for individuals with OUD using fentanyl
18 years - 99 years
All genders
If you are struggling with illicit fentanyl use, a new clinical research study is available for you. The purpose of this research study is to determine whether a new approach to starting buprenorphine ("Suboxone") has less withdrawal than the standard approach. This new approach is called rapid low dose initiation. Another …
NEUROBIOLOGICAL CORRELATES OF AUTOBIOGRAPHICAL MEMORY TRAINING TO IMPROVE OPIOID USE DISORDER OUTCOMES
18 years - 60 years
Accepts healthy volunteer
All genders
The study is being conducted with healthy control individuals and people with opioid use disorder (OUD) to better understand brain and memory functioning in people with OUD. The study will test whether a 4-week memory training intervention (Memory Flexibility Training) improves memory in people with OUD.
Can Psilocybin Improve Brain, Behavioral, and Clinical Outcomes in Opioid Use Disorder (OUD)?
18 years - 65 years
All genders
Phase 1
Study OverviewWe are looking for 36 people who are currently on medication-assisted treatment (MAT) for opioid use disorder (OUD) to take part in a research study. The goal is to see if a study medication called PEX010 (25 mg/day) has any effects on brain function, thinking skills, and health outcomes.Participants …
18 years - 75 years
All genders
Phase 3
The study is designed to evaluate the efficacy and safety of brenipatide verse placebo in adults with mild alcohol use disorder (AUD). This study will investigate the effects of brenipatide across a wide dose range to inform further clinical development of the molecule for the treatment of AUD.
18 years - 75 years
All genders
Phase 3
Study is designed to evaluate the efficacy and safety of brenipatide in adults with moderate-to-severe alcohol use disorder (AUD). This study will investigate the effects of brenipatide across a wide dose range to inform further clinical development of the molecule for the treatment of AUD.
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