Found 40 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to characterize the differences in the aortic valve and aortic root anatomy in patients with BAVs in order to better understand the anatomical features that allow the BAV to function normally. With this information, surgeons and cardiologists will be better able to determine which …
This is a multicenter, randomized, quadruple-blind, sham controlled, 2-part, embedded IDE clinical trial. The main objective is to evaluate the efficacy and safety of Cardiac Contractility Modulation (CCM) therapy in patients with symptomatic HF with LVEF 40-60%. The study is divided into 3 phases, screening, randomization (where 2/3 will be …
To evaluate the efficacy of NTLA-2001, as measured by the composite risk of CV-related mortality and CV events (urgent HF visits and hospitalizations due to HF, MI, arrhythmia, or stroke), compared to placebo Composite endpoint comprising Cardiovascular related mortality and frequency and timing of Cardiovascular events (urgent Heart Failure visits …
This study investigates high-risk pulmonary embolism.The study evaluates the effectiveness and safety of an investigational device compared to standard care for individuals with this condition.Who can participate: Adults aged 18 and older with a specific type of pulmonary embolism can participate. Key factors include evidence of a clot in the …
This is a single arm, multi-center device registry study capturing de-identified data on a minimum of 500 subjects with peripheral artery disease (PAD). The objective of this registry is to collect observational data under local standard of care and evaluate safety and performance of the Serranator® in treatment of peripheral …
This study investigates the use of an investigational antibiotic-eluting bioenvelope during cardiac implantable electronic device (CIED) procedures. The purpose of this study is to gather data from participants who receive this bioenvelope during their CIED implantation or replacement.The study focuses on evaluating the safety and effectiveness of the antibiotic-eluting bioenvelope. …
The AG10-501 ACT-EARLY study is a randomized, multicenter, double-blind, placebo-controlled study of acoramidis for prevention of ATTR. The objective of this study is to evaluate if the use of acoramidis as a prophylactic intervention in individuals who are carriers of a known pathogenic TTR variant but with no clinical evidence …
This study investigates ATTR amyloidosis with cardiomyopathy. The purpose of this study is to evaluate the effects of an investigational medication compared to a placebo.This study evaluates the safety and effectiveness of the investigational medication on cardiovascular events and patient-reported health status.Who can participate: Adults with a diagnosis of ATTR …
This is a post-market, prospective, multi-center, two-arm randomized-controlled clinical study. Subjects will be randomized in a 1:1 ratio into two arms: a treatment arm (use of vMap system in addition to pulmonary vein isolation [vMap+PVI]) and a control arm (PVI alone).The study is designed to compare clinical outcomes following use …
This is an observational, prospective, multi-center, non-randomized, real-world registry designed to obtain clinical experience with the FARAPULSE Pulsed Field Ablation System for the treatment of atrial fibrillation (AF). All types of AF including paroxysmal, persistent and long standing persistent may be included. Patient assessments will occur at pre- procedure, procedure, …
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