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Found 17 Soft Tissue Sarcoma trials

A listing of Soft Tissue Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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ADDS-UP3: Atopic Dermatitis Disparities Study – University of Pennsylvania and Philadelphia Partnership
18 years - 100 years
All genders
Study Overview: Join our ADDS-UP3 year-long study of adults with eczema (i.e., atopic dermatitis) in Philadelphia. The purpose of this study is to understand how your environment, including the things you come into contact with in your daily life and your everyday experiences, affects your skin.Study Details: We are asking you to …
5 years - 40 years
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication combined with high-dose ifosfamide in treating children and adults with relapsed or refractory sarcomas. The investigational medication is known to inhibit certain proteins, such as MET and VEGFR2, which are involved in tumor growth. The purpose of the study …
99 years or below
All genders
This study will: -- Collect tissue and body fluid specimens for immediate analysis and short-term storage while protecting the confidentiality of individuals undergoing resection of soft tissue sarcoma and GIST -- Correlate relevant clinical characteristics for the identification of significant tumor and immune cell markers that may have impact on …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of combining an investigational medication with chemotherapy to treat patients with certain types of sarcomas that have spread or cannot be surgically removed. The purpose of this study is to determine if adding the investigational medication to standard chemotherapy can improve outcomes for patients with …
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication in treating patients with Kaposi sarcoma. The purpose of this study is to evaluate how well the investigational medication works by blocking certain enzymes needed for tumor cell growth, which may stop the tumor from growing.Participants will receive the investigational medication …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates the effect of adding radiation therapy to the usual maintenance therapy with an investigational medication in patients with extensive stage small cell lung cancer. This study aims to compare the progression-free survival and overall survival of patients receiving the investigational medication alone versus those receiving it with …
18 years or above
All genders
Phase 1
Interventional
This study investigates the use of an investigational drug called ziftomenib in combination with standard treatments for patients with acute myeloid leukemia (AML). This study focuses on patients with specific genetic changes, such as NPM1 mutations or KMT2A rearrangements, and includes those who are newly diagnosed as well as those …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of preoperative chemotherapy followed by surgery compared to surgery alone in patients with high-risk retroperitoneal sarcoma, specifically dedifferentiated liposarcoma (DDLPS) and leiomyosarcoma (LMS). The study aims to determine if adding chemotherapy before surgery can improve disease-free survival for these patients.Participants in the study will be …
UPCC 22921 An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
12 years - 85 years
All genders
Phase 1
Interventional
This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
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