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Found 50 Birth Defects trials

A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Interventional
This study investigates the use of behavioral economics and implementation science to improve the delivery of genomic medicine within a diverse health system. The purpose of this study is to explore how non-geneticist clinicians and patients can be encouraged, through nudges, to utilize genetic testing in situations where it can …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the condition of locally advanced or metastatic solid tumors. It evaluates an investigational medication to understand its effects on this particular health issue.The purpose of this study is to evaluate the safety and effectiveness of the investigational medication. It assesses how well the medication is tolerated and …
18 years or above
All genders
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
18 years or above
All genders
Phase 2
Interventional
This study investigates primary central nervous system lymphoma. The purpose of this study is to evaluate the safety and efficacy of an investigational medication as a first-line treatment for individuals who cannot undergo a transplant.The study evaluates the effectiveness and safety of the investigational medication in patients. It focuses on …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
18 years - 99 years
All genders
Interventional
This study investigates the use of a medical device containing yttrium-90 for treating liver cancer, specifically Hepatocellular Carcinoma (HCC). The purpose of this study is to evaluate the safety and effectiveness of Eye90 microspheres, which deliver localized radiation therapy directly to liver tumors. This approach is used for patients whose …
18 years or above
All genders
Interventional
This study investigates the use of investigational supplementation as a potential strategy to slow down the development and growth of intestinal adenomas in individuals with Familial Adenomatous Polyposis (FAP). The study aims to explore whether this supplementation can reduce the frequency of medical procedures like endoscopies and possibly delay the …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effects of an investigational radioligand therapy in adults with advanced or metastatic solid tumors that have high levels of fibroblast activation protein (FAP). The study aims to understand how the investigational therapy interacts with FAP. The purpose of this study is to evaluate the …
50 years - 75 years
All genders
Observational
This study investigates different methods for monitoring pancreatic cysts. Monitoring these cysts is important to prevent complications. The purpose of this study is to compare two approaches: more frequent monitoring versus less frequent monitoring, to see which one leads to better outcomes for patients with pancreatic cysts.Participants in the study …
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