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Found 50 Birth Defects trials
A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates a treatment for liver metastases from neuroendocrine tumors. It aims to find the best dose and safety of a hypoxia-activating agent combined with embolization, a procedure that blocks blood flow to cancer cells. The agent, administered directly into the liver's arteries, is evaluated using MRI scans based …
This study investigates the use of an investigational oncolytic immunotherapy called RP2 in combination with other treatments for patients with advanced liver and biliary tract cancers. Specifically, it looks at patients with hepatocellular carcinoma (HCC) that cannot be surgically removed or has returned or spread, and biliary tract cancer (BTC) …
This study investigates providing access to axicabtagene ciloleucel, an investigational medication, for patients who have a disease approved for treatment with this medication but whose product does not meet commercial release criteria. The purpose is to allow patients to receive treatment with axicabtagene ciloleucel that is otherwise unavailable due to …
This study investigates the safety and efficacy of an investigational medication, surovatamig, administered alone or with other anticancer agents in individuals with mature B-cell malignancies. This study is open-label, meaning both researchers and participants know what treatment is being administered. It includes three substudies, each focusing on different types of …
This study investigates the use of an investigational therapy for patients who have been diagnosed with a condition approved for treatment with this therapy, but whose therapy does not meet commercial release criteria. The purpose is to provide access to this investigational treatment under specific conditions.Participants in this study will …
This study investigates the safety and effectiveness of an investigational imaging agent in female patients who are undergoing surgery for ductal carcinoma in situ (DCIS) or early-stage breast cancer. The purpose of this study is to understand how the imaging agent works in the body and its potential to aid …
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
This study investigates the long-term safety of investigational cell therapies in patients who have previously participated in Caribou-sponsored clinical studies, special access programs, or investigator-initiated trials (IITs). The purpose of this study is to observe patients over a period of up to 15 years after they have received their initial …
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
This study investigates the safety and effectiveness of an investigational medication in patients with relapsed or refractory leukemias, including those with specific genetic changes such as MLL/KMT2A gene rearrangement or NPM1 mutation. The study is divided into two phases: Phase 1 aims to find the best dose of the investigational …
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