Found 50 Birth Defects trials
A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The primary objective is to establish the merit and feasibility of QUTE-CE MRI vascular imaging biomarkers for detecting vascular abnormalities in (n=10) patients with TBI at least 6 months after injury compared to (n=10-16) healthy control (HC) subjects using IV Ferumoxytol as a contrast agent. The single timepoint visit includes: …
This study employs a multi-center approach to evaluate cutaneous vasculitis across several forms of idiopathic vasculitis. Patients with cutaneous manifestations of vasculitis will be evaluated by teams of primary vasculitis care providers and Dermatologists in order to facilitate optimal selection of patients and sampling of lesions. A punch skin biopsy …
This study investigates fibrotic conditions. It uses Fibroblast Activating Protein (FAP) PET/CT imaging to look at fibrosis caused by different medical conditions.The study evaluates if this imaging method can show how fibrosis affects major organs and tissues. It focuses on understanding the distribution of FAP in the body.Who can participate: …
Test Trial for Go-Live for data migration - testExclusion Criteria:The presence of any active, known, or suspected autoimmune disease. Type 1 diabetes, which was admitted to receive stable dose of insulin, hypothyroidism, which required only hormone replacement therapy, skin disease with no need to systemic treatment and no acute exacerbation …
Primary Objective: To compare the efficacy of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from baseline in 28-day average seizure frequency. Secondary Objcetives: -To compare the efficacy of 2 doses of BHV-7000 to placebo as adjunctive therapy …
This natural history study will collect data to contribute to the development of future novel therapies that focus on the neuropathophysiological features that underlie ALSP and that are essential to reverse, delay, or stop progression of this debilitating disorder.
This is a randomized, masked, multicenter clinical trial with allocation to two treatment arms with early intratracheal administration of a combination of budesonide with surfactant (Intervention), as compared to surfactant alone (Control) to reduce the incidence of physiologic bronchopulmonary dysplasia (BPD) in extremely preterm infants. To be included, the infant …
This research study seeks to validate how echocardiogram (echo) data predicts response to cardiac resynchronization therapy (CRT) provided by a CRT device with a defibrillator (CRT-D) in individuals without the heart arrhythmia abnormality left bundle branch block (LBBB). It also aims to identify new variables recorded from electrocardiograms (ECG) or …
PURPOSE: The objectives of the study are to recruit patients with GI NETs and to develop an annotated database including biosamples for use by our research group including biosamples to facilitate better understanding of the genetics and biochemical signaling pathways leading to tumor formation and malignancy. Our first project is …
This research study is being conducted to collect information on those who have been diagnosed with a disease related to a heart valve dysfunction or abnormality, needing surgical repair, or replacement of the affected valve. This research study is collecting information about the disease and the treatment. Participants will be …
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