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Found 79 Chemotherapy trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 08821 Evaluating in vivo PARP-1 expression with 18F-FluorThanatrace positron emission tomography (PET/CT) in Patients with Metastatic Prostate Cancer
18 years or above
Male
Observational
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
UPCC 02110 I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And Molecular Analysis 2)
18 years or above
All genders
Phase 2
Interventional
This study investigates personalized medicine approaches to determine which investigational medications are most effective for different types of breast cancer tumors. The purpose is to identify early indicators of treatment response, such as tumor analysis before surgery using MRI images, tissue, and blood samples, to predict treatment success.Participants will undergo …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of a combination of investigational medication and PD-1 inhibition on recurrent IDH-mutant glioma, a type of brain tumor. The purpose of this study is to see if this combination can stimulate an immune response against the tumor.Participants in this study will undergo different procedures depending …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
18 years - 120 years
Accepts healthy volunteer
All genders
This study investigates whether primary palliative care can serve as an alternative to specialty palliative care in improving the quality of life, symptoms, mood, coping, and end-of-life outcomes for patients with acute myeloid leukemia (AML). These patients face a sudden, life-threatening diagnosis requiring immediate hospitalization and treatment, which can cause …
UPCC 10120 A Single Arm Phase 2 Trial of Atezolizumab with Sacituzumab Govitecan to Prevent Recurrence in Triple Negative Breast Cancer (ASPRIA)
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of two investigational medications to treat residual triple negative breast cancer. The purpose of this study is to see if the combination of sacituzumab govitecan and atezolizumab can be effective for patients who have residual cancer in the breast or lymph nodes and have circulating …
UPCC 16121 Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-Negative Metastatic Triple Negative Breast Cancer (TNBC)
18 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effectiveness of an investigational treatment for patients with metastatic triple-negative breast cancer (TNBC) that is PD-L1-negative. The purpose of this study is to evaluate Sacituzumab Govitecan, alone or in combination with Pembrolizumab, in delaying the progression of this cancer.Participants will undergo various study procedures, …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of combining hormone therapy with or without an investigational medication in treating patients with breast cancer. Hormone therapies like tamoxifen citrate and others work by lowering estrogen levels, potentially slowing or stopping cancer growth. The investigational medication being studied may also stop tumor growth by …
18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational treatment, rapcabtagene autoleucel, for different types of blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), and high-risk large B-cell lymphoma (HR LBCL).The study consists of two phases. In Phase I, …
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