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Found 60 Chemotherapy trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
18-39 years
All genders
Phase 3
Interventional
The first purpose of this study is to test the safety of the addition of a drug called inotuzumab to the usual chemotherapy drugs used for adolescent young adults (ages 18-39). Inotuzumab is investigational and is not FDA-approved. Additionally,this study is to compare any good and bad effects of using …
99 years and younger
All genders
PURPOSE Our aim is to create a comprehensive glomerular disease database at the Hospital of the University of Pennsylvania. The database will aid researchers in rapid selection of patients for recruitment to multi-center studies and trials and allow basic characterization of patients. The databank will have 2 parts A. an …
99 years and younger
All genders
Phase 1
This research study is being conducted to evaluate an experimental drug called CART EGFR-IL13Ra2 cells in patients with glioblastoma that has returned or worsened on current treatment.
 A Randomized Study Comparing Venetoclax and Azacitidine to Induction  Chemotherapy for Newly Diagnosed Fit Adults with Acute Myeloid Leukemia
18-99 years
All genders
Phase 2
Interventional
This research is being done to see how an investigational combination of study drugs works in comparison to chemotherapy in people with acute myeloid leukemia. This study involves the following study drug combinations. You will only receive one of these combinations: • Venetoclax and azacitidine (investigational combination) • Cytarabine and …
99 years and younger
All genders
Investigate the efficacy and safety of luveltamab tazevibulin compared to IC chemotherapy in subjects with relapsed platinum-resistant epithelial ovarian cancer expressing FOLR1. Luveltamab tazevibulin is an antibody-drug conjugate (ADC) targeting FOLR1 which is expressed in approximately 80% of recurrent ovarian cancers, and expression is maintained in metastatic foci and in …
99 years and younger
All genders
This study is being done to answer the following questions: Does starting treatment with the immunotherapy drug, MK-3475 (pembrolizumab), alone, instead of a combination of immunotherapy and chemotherapy, result in a significant improvement in overall survival (OS) (time being alive) for patients with your type of cancer? Does additional treatment …
 A Umbrella Study with Rolling Arms of Investigational Agents with Pembrolizumab in Combination with Chemotherapy in Treatment-Naive Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
18-99 years
All genders
Phase 2
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the substudies. This substudy examines investigational agents (MK-7684, MK-5890, MK-4830) in combination with pembrolizumab plus standard chemotherapy in treatment-naïve participants with advanced NSCLC.
 Destination Therapy Post Approval Study Product Surveillance Registry Platform Addendum and Apogee
99 years and younger
All genders
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Adjuvant Chemotherapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1  BRCA2 or PALB2 Mutation
18-99 years
All genders
The purpose of this study is to compare the usual treatment alone to using one year of olaparib. We will enroll subject who have been diagnosed with pancreatic cancer and have undergone surgery to remove the cancer. Only patients who are found to have a BRCA1, BRCA2 or PALB2 mutation …
 Study to Evaluate the Safety  Tolerability  and   Preliminary Efficacy of XmAb 20717 Alone or in Combination with Chemotherapy or Targeted Therapies in  Selected Subjects with Metastatic Castration-Resistant Prostate Cancer
18-99 years
All genders
The primary purposes of this research study are to determine the safety and tolerability of XmAb20717 by itself and in combination with other anticancer therapies. Subjects are being asked to take part in this research study because they have metastatic castration resistant prostate cancer (mCRPC), a prostate cancer that has …
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