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Found 79 Chemotherapy trials
A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of an investigational drug called ziftomenib in combination with standard treatments for patients with acute myeloid leukemia (AML). This study focuses on patients with specific genetic changes, such as NPM1 mutations or KMT2A rearrangements, and includes those who are newly diagnosed as well as those …
This study investigates the effectiveness of adding adjuvant chemotherapy to ovarian function suppression and endocrine therapy in premenopausal patients with early-stage, estrogen receptor-positive, HER2-negative breast cancer. The study focuses on patients with specific Oncotype recurrence scores, which help predict the risk of cancer returning.Participants in the study will receive ovarian …
This study investigates how effective one year versus two years of maintenance therapy is for patients with advanced ovarian cancer that has BRCA1/2 mutations or is homologous recombination deficient (HRD+). The purpose is to compare the effects of using the investigational medication, olaparib, with or without an antiangiogenic agent, bevacizumab, …
The purpose of this study is understand changes in cognition, physical abilities, and quality of life of individuals receiving venetoclax-based chemotherapy.
This study investigates the effects of an investigational medication in combination with chemotherapy for adults with newly diagnosed FLT3-ITD negative acute myeloid leukemia (AML). This trial will compare the investigational medication to a placebo to see if it improves overall survival in these patients.Participants will receive either the investigational medication …
This study investigates the effectiveness and safety of an investigational medication activated by radiotherapy, with or without cetuximab, for elderly patients who cannot receive platinum-based chemotherapy. The focus is on individuals with locally advanced head and neck squamous cell carcinoma (LA-HNSCC). Participants are divided into two study arms to compare …
This study investigates treatment options for patients with non-small cell lung cancer (NSCLC) that have mutations in the epidermal growth factor receptor (EGFR) gene. Patients in this study have experienced disease progression despite previous treatment with EGFR tyrosine kinase inhibitors, which are medications that block signals promoting cancer cell growth.Participants …
This study investigates non-small cell lung cancer. This study looks at how adding an investigational medication to the usual treatment affects patients with this condition.The study evaluates the safety and effectiveness of the investigational medication when used with standard treatments. It observes how well the treatment works and any side …
This study investigates the safety, tolerability, and preliminary effects of an investigational medication combined with gemcitabine in patients with advanced pancreatic cancer. The study is for those who have already been treated with chemotherapy that includes 5-fluorouracil and have not responded to it.Participants will first receive a single dose of …
This study investigates treatment options for non-small cell lung cancer (NSCLC), focusing on patients who undergo surgery. The purpose is to determine if adding an investigational medication to pembrolizumab post-surgery is more effective in preventing disease recurrence in patients who did not achieve a pathological complete response (pCR) after initial …
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