Found 79 Chemotherapy trials
A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the efficacy and safety of an investigational medication in adults with relapsed or refractory indolent B-cell Non-Hodgkin Lymphoma (NHL), specifically follicular lymphoma (FL) and marginal zone lymphoma (MZL). The purpose of this study is to understand how well the investigational medication works in treating these types of …
This study investigates the use of investigational immunotherapy called Chimeric Antigen Receptor T Cells (CAR T Cells) for patients awaiting kidney transplantation. These patients have a high calculated Panel Reactive Antibody (cPRA) of 99.5% or higher, indicating a likelihood of rejecting most available kidneys. The study aims to determine if …
This study investigates the effectiveness of adding investigational medication combinations to the usual chemotherapy in patients with HER2 positive endometrial cancer. The investigational medications, which include monoclonal antibodies like trastuzumab and pertuzumab, target HER2 receptors on cancer cells to block signals for growth and potentially mark the cells for destruction …
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
This study investigates an investigational medication for people with advanced cancers that are positive for the PRAME protein. The study aims to understand the safety and effectiveness of this investigational medication in adults who have a specific genetic marker called HLA-A*02:01 and PRAME-positive tumors.Participants in this study will receive the …
This study investigates an investigational medication for patients with advanced non-small cell lung cancer (NSCLC) and other solid tumors that have a specific change in the anaplastic lymphoma kinase (ALK) gene. The purpose of this study is to find out how safe and tolerable the investigational medication is, and to …
This study investigates an investigational therapy using autologous CAR T-cells targeting Cadherin 17 (CDH17) for patients with advanced gastrointestinal cancers. These cancers have either returned after treatment or did not respond to standard treatments. The study aims to evaluate the safety and effectiveness of this therapy in patients with specific …
This study investigates the effects of total ablative therapy compared to usual systemic therapy in patients with limited metastatic colorectal cancer. Colorectal cancer can spread to other parts of the body, and this study focuses on cases where it has spread to up to four sites. Ablative therapy aims to …
This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
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