Found 390 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effects of adding an investigational medication, a type of immunotherapy, to chemotherapy before surgery in patients with high-grade upper tract urothelial cancer. Immunotherapy uses substances to stimulate or support the immune system to fight cancer, while chemotherapy uses drugs to kill or slow the growth of …
This study investigates screening methods for pancreatic cancer in individuals who are at high risk due to genetic factors or family history. The purpose of this study is to better understand the effectiveness of these screening methods in detecting early signs of pancreatic cancer.Participants in this study will undergo procedures …
This study investigates hematologic malignancies. The purpose of this study is to assess the safety and feasibility of using autologous anti-CD45 CAR T cells in combination with CD45 base edited hematopoietic stem and progenitor cells.The study evaluates the effectiveness and safety of these treatments in patients who have relapsed or …
This study investigates the safety, tolerability, and effects of an investigational medication in individuals with blood cancers that have not responded to previous treatments. The purpose of this study is to determine how well the investigational medication works when used alone or in combination with other anticancer agents. Participants will …
We propose the use of 2 different study populations to first evaluate cancer access outcomes among patients enrolled in IMPaCT who subsequently receive a diagnosis of cancer, compared to University of Pennsylvania Health System administrative data of cancer patients not enrolled in IMPaCT who meet insurance and zipcode criteria; and …
This study investigates the use of PET/CT imaging to evaluate the uptake of a special substance called [18F]F-Gln in patients with breast cancer. This study includes patients with known or suspected primary or metastatic breast cancer, which means the cancer may have spread to other parts of the body. The …
This study investigates the safety and effectiveness of an investigational medication in patients with advanced blood cancers, including Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukemia, and high-risk Myelodysplastic Syndrome.Participants in the study will receive the investigational medication either alone or in combination with other treatments. The study will monitor the …
This study investigates relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes. It focuses on understanding the effects of an investigational medication called AUTX-703.The study evaluates the safety, tolerability, and how the body processes and responds to AUTX-703. It looks at how effective the investigational medication is in treating the conditions.Who can …
This study investigates a targeted palliative care program for individuals with metastatic breast cancer and their caregivers. The aim of this study is to enhance communication between patients, caregivers, and clinicians about the patients' goals and preferences for care.Participants in the study will be randomly assigned to receive either the …
This study investigates the effectiveness of an investigational medication combined with chemotherapy compared to another treatment with chemotherapy for patients with advanced non-small cell lung cancer. The focus is on those with a specific protein expression called PD-L1. The study aims to understand how well the investigational medication works in …
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