Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Primary Objective: To determine changes in neurodegeneration over the first year of treatment with anti-amyloid monoclonal antibodies Secondary Objectives: To identify measures that detect and monitor neuroinflammation during anti-amyloid treatment. To explore the interaction between neuroinflammation and neurodegeneration Primary Endpoint: Neuroimaging and blood-based measures of neurodegeneration, cognitive performance Secondary Endpoints: …
3 OBJECTIVES AND ENDPOINTSPrimary and secondary outcomes will be assessed using routinely collected electronic health record data at Penn Medicine Princeton Medical Center, Pennsylvania Hospital, and Penn Medicine Lancaster General Hospital. Exploratory outcomes will be assessed among those consenting to correlative analyses using additional data collected from participant step count …
This study investigates the safety and feasibility of using a type of adoptive cell therapy called CAR T cells in patients with FRa+ cancers. The purpose of this study is to assess how well these modified T cells can be administered directly into the pleural space, which is the area …
This study investigates hematopoietic cell transplantation and other cellular therapies, as well as marrow toxic injuries. The purpose is to collect observational data to better understand these conditions.The study will gather data from participants who undergo routine care, without altering their treatments. This observational study aims to create a comprehensive …
Investigate the involvement of the microbiome and associated metabolites in ovarian cancer. Generate a predictive model for ovarian cancer risk and progression. The primary outcome variable is metabolite identification and analysis. The secondary outcome variable is cancer risk as related to metabolites and genetic variants.
The goal of the eREACH3 Study is to evaluate the implementation of digital tools into remote genetic services, evaluating uptake and use of digital tools and outcomes in representative clinical populations. Our primary endpoints will include uptake of services and digital alternatives (future amendments). We will use proportions and 95% …
All objectives are listed in section 3 of the protocol, but the primary objective is to evaluate the long-term safety of RAP-219 in participants with focal onset seizures. The primary endpoint is the incidence of treatment-emergent adverse events (TEAEs). The secondary objectives and their associated endpoints can be found in …
This study investigates the effects of an investigational medication compared to a placebo in participants with myocarditis linked to immune checkpoint inhibitors (ICI). This condition can occur as a side effect of cancer treatments that use ICIs to enhance the body's immune response against cancer cells. The purpose of this …
In this secondary use protocol, we will analyze de-identified data from a funded VA study called the Veterans Affairs Multi-omic Platform for Prostate Cancer (VA-MAPP) shared with our team through a fully executed data use agreement with the Greater Los Angeles VA and Penn Medicine to study the genetics of …
PRIMARY OBJECTIVE: To conduct a multicenter, observational study of patients with well-characterized hepatic adenoma. At the end of the study, robust clinical information, central bio-repository of genomic DNA and liver tissue (where available) will be developed SECONDARY OBJECTIVE: To develop the well characterized hepatic adenoma biorepository with linked clinical data …
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