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Found 66 Metastatic Cancer trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

GOG 3096: Dose Optimization and Phase 3 Study of R-DXd versus Investigators Choice of Chemotherapy in Platinum-resistant Ovarian Cancer

99 or below
All genders
Phase 2: To evaluate BICR-assessed objective response rate at each dose level of R-DXd. Phase 3:To evaluate BICR-assessed objective response rate with R-DXd treatment compared with investigator's choice of paclitaxel, PLD, gemcitabine, or topotecan. Objectives, outcome measures, and endpoints are located in Tables 3.1 and 3.2 of the protocol. Phase …
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11C-M503 PET

99 or below
All genders
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C M503 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C M503 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
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BCG at home

99 or below
All genders
The long-term goal of our research program is to identify and target the mechanisms by which innovations in care delivery may facilitate compliance with guideline-concordant care and access to care for early and late stage bladder cancer patients. The objective in this proposal is to evaluate a novel delivery model …
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11C-HY-2-15 PET

99 or below
All genders
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C HY-2-15 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C HY-2-15 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
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PHOENIX-HNSCC

99 or below
All genders
PURPOSE To create a robust multi-omic dataset composed of rich molecular and clinical data for metastatic or unresectable, recurrent HNSCC patients who receive standard of care immune checkpoint inhibitors therapy for the purposes of understanding the relationship between biomarkers and real-world outcomes of standard of care therapies. The primary objective …
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Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

99 or below
All genders
Please refer to protocol section 3 for information on study objectives. Overall objectives include: Objective 1: Determine the efficacy of letermovir for preventing CMV infection in thoracic organ transplant recipients as compared to valganciclovir prophylaxis Objective 2: Determine the tolerability of letermovir for CMV prophylaxis among heart and lung transplant …
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GE 280-401

99 or below
All genders
Primary Objective: a) To measure the proportion of breast cancer patients where Cerianna positron emission tomography (PET)/computed tomography (CT) detection of estrogen receptor (ER) status alters the preexamination intended therapeutic management Secondary Objectives: a) Per subject, to qualitatively assess heterogeneity in tumor Cerianna uptake relative to standard-of-care imaging b) Per …
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TcMS Approaches for VT

99 or below
All genders
Primary: To determine whether TcMS can reduce the burden of VT in patients with VT storm. Secondary: 1. To determine whether low frequency TcMS or TcMS with TBS is more effective at reducing the burden of VT in patients with VT Storm. 2. To determine the safety of TcMS in …
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Caron Ketone AUD withdrawal study

99 or below
All genders
To examine the effects of ketone supplement, Kenetik (KS) three times daily (TID), verse placebo, on the need for benzodiazepines and CIWA scores, while undergoing in-patient acute withdrawal management.To test the effects of Ketone Supplementation (KS) Kenetik in reducing alcohol withdrawal signs and symptoms and the need for medications to …
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LeMi EPL Protocol

99 or below
All genders
Objective 1: Estimate efficacy of medical management with oral letrozole 10 mg daily for three consecutive days followed by vaginal misoprostol 800 mcg for treatment of EPL Objective 2: Assess side effects, adverse events, and patient acceptability associated with letrozole and misoprostol for medical management of EPL Our primary outcome …
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