Found 66 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
Specific Aim 1: To image the intracranial artery vessel walls (brain), we will evaluate and compare scans acquired using standard-of-care T1 SPACE and T1 MPRAGE sequences with novel accelerated pulse sequences in patients with suspected intracranial vasculopathy. Specific Aim 2: To image the extracranial artery vessel walls (neck). We will …
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …
The objectives of the study are:To investigate demographic, clinical, genetic, and environmental factors that contribute to variability in analgesic response to ibuprofen.To compare the inflammatory profile and neutrophil phenotypes between patients who use supplemental opioids and those who do not.To establish a well-phenotyped cohort of subjects, with biobanked samples, that …
Primary Objectives:To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer [18F]Fluciclovine and 18F-FDG PET. Secondary Objectives:To compare uptake measures of 18F-Fluciclovine and 18F-FDG and MRI quantification of glutamate and lactate levels to tumor tissue laboratory assays (RNA seq and proteomics) of glutamine/glutamate, glucose, and lactate metabolism. To …
The primary study objective is to evaluate the rate of durable remission of relapsing disease activity, assessed serially both clinically and by MRI, from randomization through 48 months in participants with early relapsing multiple sclerosis who discontinue OCR after 12 and 24 months of treatment. Secondary objectives include: - Mechanistic: …
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
PRIMARY OBJECTIVE: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with IV echinocandin followed by oral ibrexafungerp is non-inferior to IV echinocandin followed by oral fluconazole based on 30-day all-cause mortality (ACM). SECONDARY OBJECTIVES: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with intravenous (IV) echinocandin followed by oral ibrexafungerp …
The objective of this study is to establish reasonable assurance of safety and effectiveness to support a premarket application (PMA) to the U.S. FDA for the Cortiva Allograft Dermis, a human acellular dermal matrix (ADM), when used on label as an adjunct in two-stage breast reconstruction. The primary safety endpoint …
This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur.
