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Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The primary objectives are to determine the pharmacokinetic (PK) and pharmacodynamic (PD) response of dorzagliatin 75 mg twice daily following 7-day administration in individuals with PI-CF and abnormal glucose tolerance (EGI, IGT or CFRD) when compared to 7-day administration of placebo according to a randomized, double-blind cross-over study design. The …
This research study will evaluate changes in chin volume following treatment with an FDA-approved hyaluronic acid filler (Restylane Lyft) manufactured by Galderma that is used as part of standard care for chin augmentation. The primary goal of the study is to measure how chin volume changes over time after filler …
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
PURPOSE We aim to conduct a prospective observational study to test the central hypothesis that myocardial LM begins early after STEMI, as a response to myocardial hemorrhage and reperfusion injury, and determines future susceptibility to malignant arrhythmia. Study participants will be 175 (allowing for 25 dropouts) men and women 2 …
Study Objectives This is an observational, non-interventional study. The goal of this project is to facilitate translational research to advance the field of acute neurology and neurosurgery by establishing a biobank of blood samples and correlating data from patients with LVO. Prior to conducting any research involving human subjects, written …
Primary Objective: To compare the efficacy of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from baseline in 28-day average seizure frequency. Secondary Objcetives: -To compare the efficacy of 2 doses of BHV-7000 to placebo as adjunctive therapy …
This study investigates heart failure due to left ventricular systolic dysfunction. It focuses on comparing two types of pacing: His bundle branch pacing and Left bundle branch pacing.The study evaluates the effectiveness and safety of these pacing methods. It looks at how they impact quality of life, physical activity, and …
The purpose of this study is to investigate primary immune thrombocytopenia. This study evaluates how well the investigational medication works with corticosteroids in maintaining platelet count in adults.The study focuses on assessing the safety and effectiveness of the investigational medication in comparison to a placebo. It evaluates how the treatment …
This study investigates the safety and effectiveness of an investigational imaging agent used during lung cancer surgery. The purpose is to see if this agent can help identify cancerous tissue using near-infrared (NIR) imaging. Participants in this study will undergo surgery for lung cancer, and the investigational agent will be …
This study investigates the safety and initial effects of an investigational medication in people with advanced or metastatic solid tumors that have changes in the MAPK pathway. The purpose of this study is to understand how the investigational medication affects these tumors and to determine the appropriate dosage for future …
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