Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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To explore secondary malignancies in subjects enrolled to the L-RAD study (IRB #832203, Lymphoproliferative Disorders: Biological Specimen Repository and Clinical Database) who received CAR T-cells or other T-cell directed therapies for lymphoproliferative disorders and to investigate potential relationships between prior T-cell directed therapy for lymphoma and subsequent malignancies.
This study investigates a treatment approach for renal cell carcinoma that has spread to other parts of the body. The purpose of this study is to evaluate the effectiveness of a specific therapy called total consolidative metastasis-and-primary directed therapy (MPDT) in patients who have shown stable disease or partial response …
This study investigates the effect of adding radiation therapy to the usual treatment for patients with high-risk asymptomatic bone metastases. These metastases are defined by their location or size, such as those that are 2 cm or larger or located in critical areas like the hip, shoulder, or spine, and …
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of this medication both as a standalone treatment and in combination with other agents. The study is focused on …
This study investigates a treatment for liver metastases from neuroendocrine tumors. It aims to find the best dose and safety of a hypoxia-activating agent combined with embolization, a procedure that blocks blood flow to cancer cells. The agent, administered directly into the liver's arteries, is evaluated using MRI scans based …
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
This study investigates the effects of additional treatment after surgery for patients with high-risk well-differentiated pancreatic neuroendocrine tumors. The purpose of this study is to see if giving the investigational medications capecitabine and temozolomide after surgery can prevent or delay the return of cancer compared to just observing the patients …
This study investigates the effects of a combination of investigational medications in patients newly diagnosed with secondary acute myeloid leukemia (AML) after previous exposure to hypomethylating agents. The purpose of this study is to understand how these investigational medications work together to treat AML.Participants in the study will receive a …
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
This study investigates the safety and effectiveness of an investigational CAR T-cell therapy in adults with metastatic prostate cancer. CAR T-cell therapy is a treatment where a patient's T-cells, a type of immune cell, are modified to better recognize and attack cancer cells. The purpose of this study is to …
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