Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study will evaluate whether the Impella 5.5 heart pump can safely support patients with severe heart failure and cardiogenic shock while doctors optimize their recommended heart failure medications. Patients at multiple hospitals will receive the device, and researchers will assess its safety and feasibility in real-world clinical use. The …
The Women's Health Clinical Research Center at Penn Medicine is conducting a paid research study to see if women with sickle cell disease (SCD) experience any pain differences while using the birth control injection known as Depo, as compared to when not using it. Depo-Provera is already FDA-approved, safe to …
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body. - Between 18–45 years old - Nicotine …
The primary objective is to evaluate the efficacy of obicetrapib alone for 8 weeks as compared to obicetrapib in combination with Evolocumab for an additional 8 weeks after initial obicetrapib treatment on percent change of Lp(a) levels from Baseline in people with mild dyslipidemia, defined as Lp(a) levels 50 mg/dL …
This study investigates idiopathic Multicentric Castleman Disease (iMCD).The study evaluates the effects of an investigational medication on iMCD symptoms and how well it is tolerated by participants.Who can participate: Adults aged 18 to 80 with a history of iMCD can participate. Key eligibility includes documented disease history, not responding to …
This study investigates cardiovascular events in individuals with elevated lipoprotein(a).It evaluates the effect of an investigational medication on the risk of heart disease-related death and other major heart events.Who can participate: Adults aged 50 and older with high lipoprotein(a) levels can participate.Study details: Participants will receive either the investigational medication …
Requesting a reliance agreement with an external IRB. The purpose of this open-label extension trial is to evaluate the long-term safety and efficacy of treatment with plozasiran on the reduction of fasting serum TG from Baseline in subjects with Severe Hypertriglyceridemia.
Requesting a reliance agreement with an external IRB. The objectives are to evaluate the long-term safety and tolerability of pelacarsen (TQJ230) in participants with elevated Lp(a) and established CVD who have completed the parent Lp(a)HORIZON study, evaluate the long-term efficacy of pelacarsen (TQJ230) on 4P-MACE, and to evaluate the long-term …
To assess the effect of donanemab versus placebo on cognitive and functional progression in participants with established alpha-synuclein and amyloid co-pathology
Test Trial for Go-Live for data migration - testExclusion Criteria:The presence of any active, known, or suspected autoimmune disease. Type 1 diabetes, which was admitted to receive stable dose of insulin, hypothyroidism, which required only hormone replacement therapy, skin disease with no need to systemic treatment and no acute exacerbation …
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