Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This is a 2-part, open-label study in approximately 9 adults with oHCM. Part A of the study consists of 3 cohorts of approximately 3 participants each administered a single dose of EDG-7500. Part B of the study is an optional multiple-dose treatment period in which approximately 9 participants will receive …
This study investigates the effects of an investigational medication on nonobstructive hypertrophic cardiomyopathy (noHCM).The study evaluates the safety and potential benefits of the investigational medication in improving exercise capacity and cardiac function.Who can participate: Adults with a diagnosis of hypertrophic cardiomyopathy who can take oral medication and comply with study …
This study investigates the safety and effectiveness of an investigational atrioventricular interval modulation (AVIM) algorithm in patients with dual-chamber pacemakers.The study evaluates how well the investigational AVIM algorithm works when downloaded into a specific type of pacemaker. It looks at whether this algorithm can be safely used and how effective …
This study investigates heart failure due to left ventricular systolic dysfunction. It focuses on comparing two types of pacing: His bundle branch pacing and Left bundle branch pacing.The study evaluates the effectiveness and safety of these pacing methods. It looks at how they impact quality of life, physical activity, and …
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The goal of the SAK study is to test whether Empagliflozin, with and without Potassium Nitrate, improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity in participants with Heart Failure with Preserved Ejection Fraction. We are assessing whether this medication and supplement, either together or separate, helps relieve symptoms …
This study investigates symptomatic hypertrophic cardiomyopathy. The condition is being studied to understand changes in symptoms and functional limitations when treated with an investigational medication compared to a placebo.The purpose of this study is to evaluate how safe and effective the investigational medication is for people with the condition. It …
PURPOSE We aim to conduct a prospective observational study to test the central hypothesis that myocardial LM begins early after STEMI, as a response to myocardial hemorrhage and reperfusion injury, and determines future susceptibility to malignant arrhythmia. Study participants will be 175 (allowing for 25 dropouts) men and women 2 …
This study investigates the use of an investigational catheter and ablation system for individuals with scar-related monomorphic ventricular tachycardia.The purpose of this study is to evaluate the feasibility of using the Sphere-9 Catheter and Affera Ablation System for treating this condition. The study will focus on assessing the safety and …
This study investigates heart failure with severely reduced ejection fraction. It will explore how the investigational medication may affect this condition.The study evaluates the effectiveness and safety of the investigational medication in reducing risks associated with heart failure, such as cardiovascular events and other serious outcomes.Who can participate: Adults aged …
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