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Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of polygenic risk scores (PRS) and novel early detection strategies in women at risk for ovarian cancer. The purpose of this study is to understand how women incorporate these tools in their decisions about cancer screening and risk-reducing surgery. Researchers will conduct qualitative interviews with …
This study investigates the treatment of non-muscle invasive bladder cancer. The purpose of this study is to explore the barriers and facilitators affecting treatment compliance and to test a Bacillus Calmette-Guerin (BCG) at-home program. Participants will be divided into two study arms: one focusing on understanding treatment compliance and the …
This study investigates the safety and effectiveness of adding RP2, an investigational treatment, to the standard chemotherapy regimen, FLOT, for patients with stage II or higher, non-metastatic gastroesophageal adenocarcinoma. The purpose of this study is to determine if injecting RP2 directly into the tumors of the stomach and esophagus, combined …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
This study investigates how cancer treatment with immune checkpoint inhibitors (ICI) can lead to the development of autoimmunity. The purpose is to understand the genetic and immune system characteristics that cause some cancer patients to experience immune-related adverse events (irAE) after receiving checkpoint inhibitor therapy.Participants will provide peripheral blood and …
This study investigates the use of a web-based eHealth intervention as an alternative to traditional in-person genetic counseling for cancer genetic testing. The purpose of this study is to explore how this approach can provide necessary genetic testing information while maintaining the quality of care. The study aims to address …
This study investigates the use of medical cannabis as part of outpatient palliative care for patients with cancer. The purpose of this study is to assess how different approaches to symptom management can affect the quality of life in cancer patients who are new to palliative care.Participants will be randomly …
This study investigates the safety of combining immunotherapy and radiation therapy for treating urothelial bladder cancer. The purpose of this study is to determine if it is safe to use both treatments at the same time, which is not the usual approach. Safety will be assessed based on any acute …
This study investigates the use of investigational supplementation as a potential strategy to slow down the development and growth of intestinal adenomas in individuals with Familial Adenomatous Polyposis (FAP). The study aims to explore whether this supplementation can reduce the frequency of medical procedures like endoscopies and possibly delay the …
This study investigates the condition of locally advanced or metastatic solid tumors. It evaluates an investigational medication to understand its effects on this particular health issue.The purpose of this study is to evaluate the safety and effectiveness of the investigational medication. It assesses how well the medication is tolerated and …
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