Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The objectives of the study are to recruit patients with tumors of the autonomic nervous system and develop an annotated database including tissue samples to facilitate research with the goal of better understanding the genetics and biochemical signaling pathways leading to tumor formation and malignancy. The primary goal of this …
The purpose of this protocol is to send the pre-collected and shelved DNA samples (parent protocol IRB #376800) from patients fitting the study eligibility requirements for genotyping at the Center for Inherited Disease Research (CIDR) at Johns Hopkins University. The samples will be used in genome-wide association studies (GWAS), which …
This study investigates the genetic risk in young adults with cancer and their relatives. The purpose is to understand how universal genetic testing can identify individuals with a higher risk of cancer who might be missed by traditional testing methods. This study involves young adult cancer patients, aged 18 to …
This is a retrospective cohort study which primarily aims to understand if a patients UGT1A1 phenotype affects patients' clinical outcomes following treatment with sacitizumab. Patients will be consented for prospective sample collection to perform genotyping. The genotyping will be performed in a research laboratory and will not be returned to …
This study investigates Li-Fraumeni Syndrome (LFS) and Li-Fraumeni-like (LFL) Syndrome, focusing on the increased cancer risk associated with changes in the TP53 gene. The purpose of this study is to collect and analyze clinical data and biological samples from patients with these conditions to better understand the relationship between genetic …
The research study is being done to look at the effect of sleep apnea surgery on different measures ofcardiovascular (heart) function in people with obstructive sleep apnea.
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo.
This is a minimal risk observational study being conducted to evaluate changes in the immune cell populations in the blood, and to learn about the normal fluctuations in these cell populations in adults over time.
Featured study
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …
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