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Found 180 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
This study aims to prospectively compare the safety, effectiveness, and clinical utility of decongestive therapy administered by the Reprieve System to optimal diuretic therapy in adult ADHF patients presenting to the ED requiring decongestion. The Reprieve System continuously monitors urine output and urine sodium concentration to identify and administer the …
99 years or below
All genders
To examine the feasibility of recruiting and evaluate before and after outcomes of breast cancer survivors to undergo a patient-centered, interdisciplinary, multimodal comprehensive rehabilitation program aimed at addressing musculoskeletal, fatigue and cognitive sequelae of their cancer treatment (chemotherapy and/or endocrine therapy). Multifactorial Memory Questionnaire APT II- Attention Process Training Questionnaire …
99 years or below
All genders
Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and feasibility of using a type of adoptive cell therapy called CAR T cells in patients with FRa+ cancers. The purpose of this study is to assess how well these modified T cells can be administered directly into the pleural space, which is the area …
45 years - 99 years
Male
The objectives of this proposal are to: 1) describe the incidence of depression and trajectory of depressive symptoms; 2) identify potential determinants of depression; and 3) characterize the consequences of depression in a large, international cohort of patients with PC and in subgroups of this population during early and late …
UPCC 28922 AbatacepT foR ImmUne checkpoint inhibitor associated Myocarditis (ATRIUM): A Phase 3, Investigator-Initiated, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Compared to Placebo in Participants with Immune Checkpoint Inhibitor Associated Myocarditis
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in participants with myocarditis linked to immune checkpoint inhibitors (ICI). This condition can occur as a side effect of cancer treatments that use ICIs to enhance the body's immune response against cancer cells. The purpose of this …
UPCC 07623 Effect of Immune Checkpoint Inhibitors on Coronary Microvasculature
18 years or above
All genders
Observational
The purpose of this study is to investigate the effects of immune checkpoint inhibitors (ICI) on the heart and circulatory system in patients with breast cancer or non-small cell lung cancer. This study focuses on understanding how these medications, which are used in cancer treatment, might impact heart health. An …
CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
Quality Improvement Assessment for Patient-Centered Community Health Worker Intervention
18 years - 99 years
All genders
The purpose of the IMPaCT Transitions program is to help low-income general medicine patients who have been cared for at the Hospital of the University of Pennsylvania or Presbyterian Hospital with the transition from hospital to a primary care clinic. The purpose of IMPaCT Home is to help low-SES patients …
A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
99 years or below
All genders
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
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