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Found 180 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
Male
Observational
The purpose of this study is to investigate prostate cancer in individuals who have a genetic risk for the disease. Prostate cancer is a common cancer in men, especially those with inherited genetic changes in certain genes like BRCA1, BRCA2, ATM, TP53, and HOXB13. These genetic changes can increase the …
18 years or above
All genders
Observational
This study investigates the impact of refractory ascites on health-related quality of life and sarcopenia. The purpose of this study is to use new survey tools to measure changes in quality of life for patients with this condition.Participants will complete quality of life questionnaires at the start of the study, …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of a radiation boost in combination with immune checkpoint blockade therapy in patients with operable breast cancer. The purpose is to determine if combining pembrolizumab, an immune therapy, with a single radiation boost is feasible and effective. The study will track changes in tumor size …
18 years or above
All genders
Phase 2
Interventional
This study investigates a limited-duration therapy approach for patients with relapsed refractory multiple myeloma who have shown a very good partial response or better after receiving teclistamab. This study aims to determine if stopping teclistamab treatment after 6 to 9 months is as effective as continuous treatment in preventing disease …
18 years or above
All genders
Observational
This study investigates circulating biomarkers in patients with pancreatic adenocarcinoma. The purpose of this study is to collect blood samples from patients to evaluate these biomarkers, which are substances that can be measured in the blood and may provide information about the cancer.Participants will undergo a procedure to collect blood …
18 years or above
All genders
Interventional
This study investigates a treatment approach for renal cell carcinoma that has spread to other parts of the body. The purpose of this study is to evaluate the effectiveness of a specific therapy called total consolidative metastasis-and-primary directed therapy (MPDT) in patients who have shown stable disease or partial response …
18 years or above
All genders
Interventional
This study investigates the presence of disseminated tumor cells (DTCs) in women who have completed treatment for primary breast cancer within the last five years and are at increased risk of relapse. The purpose is to identify markers that could indicate the likelihood of breast cancer returning. This study will …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of combining an investigational medication with another treatment for patients with metastatic colorectal cancer that primarily affects the liver. In this study, researchers are looking at how the combination treatment works and its safety for patients.Participants in the study will receive the investigational medication along …
UPCC 11125: The MILES Study: A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer Survivorship
18 years or above
Female
Interventional
This study investigates breast cancer. It focuses on understanding lifestyle and energy balance in women during early treatment stages.The study evaluates dietary quality and physical activity over time. It also looks at how these factors can support healthy behaviors in patients.Who can participate: Adult women aged 18 years or older …
18 years or above
Accepts healthy volunteer
All genders
This study investigates the use of investigational medications, specifically pembrolizumab alone or in combination with lenvatinib, for treating high risk renal cell carcinoma. The purpose of this study is to see how these medications affect the immune system's response to the cancer when given before and after surgery to remove …
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