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Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The primary objective of this trial is to test whether FFRangio®-guided treatment is noninferior to conventional pressure wire-guided treatment in patients with coronary artery disease being evaluated for percutaneous coronary intervention (PCI) with respect to major adverse cardiac events (MACE) at one year
This is a randomized, response-adaptive, duration/dose finding, comparative effectiveness clinical trial with blinded outcome assessment for post-cardiac arrest patients to characterize the duration response curve for hypothermia and determine in each of two populations: the shortest duration of cooling that provides the maximal treatment effect, and whether the duration-response implies …
Please see section 2.3 of the full protocol Please see section 2.3 of the full protocol Please see section 2.3 of the full protocol
The objectives of the study are to quantify uptake and release by the brain of approximately 277 metabolites by quantitative mass spectrometry. Change in metabolite concentration between arterial and venous samples.
To determine the response of SkM OxPhos to supplemental oxygen in HFpEF noting that an increase in SkM OxPhos with supplemental oxygen suggests the presence of mitochondrial functional reserve. Change in SkM OxPhos on CrCEST in response to supplemental oxygen Change in intramuscular perfusion with supplemental oxygen as compared to …
Please see section 2 of the protocol Please see section 2 of the protocol Please see section 2 of the protocol
The objectives of the study are to quantify cardiac metabolic consumption of approximately 100 metabolites, measurable by quantitative mass spectrometry. The metabolic consumption of the heart will be measured in patients with heart failure who are simultaneously undergoing invasive hemodynamic assessment via right heart catheterization. Quantitative measurement of metabolites. None.
The aims of this study are four-fold: (1) To determine if cholate clearance is related to underlying cardiovascular hemodynamics, specifically low CO, elevated CVP, desaturation as seen in the Fontan. (2) To characterize Fontan patients with elevated systemic HFR/portal HFR ratio. (3) To know whether cholate clearance is a reliable …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
This study investigates the use of telehealth strategies to improve shared decision-making (SDM) visits for lung cancer screening (LCS). Lung cancer screening often involves low-dose computed tomography (LDCT), which can reduce lung cancer mortality but also carries risks. Patients are recommended to complete an SDM visit to discuss these risks …
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