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Found 61 neurology trials

A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years - 99 years
All genders
Observational
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD). To investigate the genetic link to PD, we will ask participants to contribute their genetic test results and associated raw data …
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Online study
65 years or above
Accepts healthy volunteer
All genders
This study aims to develop a tool to help primary care providers detect memory and thinking changes earlier using video and audio from patient visits.
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Online study
A Multicenter Randomized Controlled Trial of Best Available Therapy versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis (BEAT-MS)
18 years - 55 years
All genders
The purpose of this study is to compare efficacy and safety of Autologous Hematopoietic Stem Cell Transplant (AHSCT) to best available therapy (BAT) in relapsing MS. Best available therapy is referring to the best available medications that are used to treat MS. Patients who agree to participate in the experimental …
PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
35 years - 75 years
All genders
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
Safety and Efficacy Study of Ravulizumab in Adults With Generalized Myasthenia Gravis
18 years - 99 years
All genders
Phase 3
Interventional
The primary purpose of this study is to evaluate the safety and efficacy of ravulizumab for the treatment of participants with generalized myasthenia gravis (gMG).
Phase 2 Randomized Controlled Trial of Sildenafil Citrate for Treatment of Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury
18 years - 70 years
All genders
Phase 2
We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
50 years - 90 years
Accepts healthy volunteer
All genders
This is a Phase II, double-blind, sham controlled, randomized, crossover, multisite clinical trial investigating the effectiveness of transcranial direct current stimulation (tDCS) coupled with naming and spelling therapy (NASP) to improve language in people with primary progressive aphasia (PPA).
99 years or below
All genders
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …
tACS Language
18 years - 85 years
Accepts healthy volunteer
All genders
The research study is being conducted to test if a form of noninvasive brain stimulation,called transcranial alternating current stimulation (tACS), will improve a person’s abilityto name objects more than fake tACS. TACS is a technique by which small electriccurrents are applied to the scalp. This creates coordinated brain activity across …
A Natural History Study of Patients with Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)
18 years - 100 years
All genders
This natural history study will collect data to contribute to the development of future novel therapies that focus on the neuropathophysiological features that underlie ALSP and that are essential to reverse, delay, or stop progression of this debilitating disorder.
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