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Found 61 neurology trials

A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
To collect and store blood samples and genetic data from all patients with PD who receive medical care at the University of Pennsylvania PDMDC to support research needs. To link biospecimens to clinical data in an encrypted database. To encourage collaboration within the University of Pennsylvania and through external collaboration. …
99 years or below
All genders
Please refer to Table 5 "Objectives and Endpoints" located on page 34 of protocol version 2.0, version date, 13May2025, for a full description of the objectives of this study. Please refer to Table 5 "Objectives and Endpoints" located on page 34 of protocol version 2.0, version date, 13May2025, for a …
18 years or above
All genders
Phase 2
Interventional
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP).The study evaluates the effects of an investigational medication on the physical functioning of adults with CIDP.Who can participate: Adults aged 18 and older with a body weight of 150 kg or less and a confirmed diagnosis of typical CIDP may participate. Participants …
99 years or below
All genders
The purpose of this clinical trial is to compare the benefits and tolerability of three medications that are FDA-approved and used for migraine preventive treatment - atogepant, a newer migraine preventive medication, propranolol, and topiramate, two older migraine preventive medications. This study will provide a head-to-head comparison of the relative …
50 years - 85 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in individuals with Parkinson's disease.The study evaluates the safety, effectiveness, and how the body processes the investigational medication. It looks at participants who are already on a stable treatment.Who can participate: Adults with early-stage Parkinson's disease on …
18 years or above
All genders
Phase 3
Interventional
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP).The study evaluates the effectiveness of an investigational medication compared to standard treatments in managing CIDP.Who can participate: Adults with CIDP on stable IVIg treatment and meeting specific health criteria can participate. Participants must have an INCAT score between 2 and 9 and …
99 years or below
All genders
The primary objective is to compare the Minder System with standard of care as a means of assisting in obtaining any of the following actionable events: diagnosis, seizure characterization, surgery evaluation, event classification, paroxysmal events, psychogenic nonepileptic seizures, or treatment effects. The secondary objectives include comparing the time to the …
99 years or below
All genders
This is a study to evaluate AB-1009 (IP under study) in adult patients with late-onset pompe disease (LOPD). LOPD is caused by a genetic mutation resulting in a decrease in the GAA enzyme, resulting in the destruction of muscle tissue. AB-1009, administered as a one-time IV dose, is an gene …
99 years or below
All genders
Longitudinal study in patients with ALS and healthy controls. The study involves questionnaires, muscle strength assessments, sample collection (CSF + blood), pulmonary testing, and assessment of disease progression. The duration is 2 years with Q4M visits for patients with ALS.
50 years - 80 years
All genders
Phase 2
To assess the ability of adalimumab as compared to placebo to reduce or prevent progression of synuclein-related neurodegeneration in persons with idiopathic REM Sleep Behavior Disorder (RBD)